Even more confused...LADA? T1? None?

[novonord]

Hi

I posted on here a few months ago, as due to my low Fasting Insulin Levels and slightly high Fasting Blood Sugar, I was worried I could have or could soon develop LADA / T1. I was told by nearly all of you who responded, that it's very unlikely I have T1 particularly.

Well, now I am worried again. I have now received my C-Peptide (done privately) results. Their range was 0.73 - 4.37 ng/mL and my result was shown as LOW, as I have a level of 0.57 ng/mL

So, I have:
1. Low Fasting Insulin - less than 2
2. Slightly high fasting BS - 5.68 mmol + higher than normal when I use my own Glucometer. 2 hrs after a meal is in the range, although has gone up.
3. Low C-Peptide - 0.57 ng/mL (0.73-4.37)
4. Normal HbA1C - 34 mmol

I had a Random BS test on Friday, so I await that result

I am thinking of having a GAD test too.

Anybody know anything about my results?

Thanks
AJ

good idea to get a GAD test and perhaps request the other two antibodies to be done at the same time.
have you or anyone in your immediate family any history of organ specific autoimmune disease, eg thyroid, type 1 dm, pernicious anaemia, addison's, coeliac disease, myasthenia....?

 

[novonord]

sorry, ignore all the above, your HbA1c is well within the normal range so you should as others have stated, nothing to worry about!

 

[Bruce Stephens]

Only your HbA1C matters. If other things were wrong, that would show in your HbA1C.

HbA1c isn't always accurate. In some people it can read too low or too high. However, the reported HbA1c seems entirely consistent with the blood glucose readings (and the other tests) so I don't think there's any reason to disbelieve it. These are all things consistent with someone who doesn't have diabetes.

 

[adz81]

HbA1c isn't always accurate. In some people it can read too low or too high. However, the reported HbA1c seems entirely consistent with the blood glucose readings (and the other tests) so I don't think there's any reason to disbelieve it. These are all things consistent with someone who doesn't have diabetes.

I read that too, about HbA1C, so didn't want to just rely on that.

 

[helli]

I read that too, about HbA1C, so didn't want to just rely on that.

However, 90% of us are very happy to rely on HbA1C because false lows are very rare.
Ok, we may also have symptoms of high blood sugars like thirst and tiredness and frequent toilet visits. Some may take finger prick readings which will be much much much higher than 5.4 - almost certainly double figures.

The most common reason for inaccuracies in HbA1C is anaemia. You don’t mention this although I suspect it was included in your blood tests.
Iron deficiency anaemia may cause a higher HbA1C whereas Hemolytic anaemia may cause a lower HbA1C.

Are you taking dapsone, sulfasalazine, ribavirin, and antiretroviral drugs or had a blood transfusion recently (and previously)? These are the only other things I found (apart from a mistake in your test which is very unlikely given your test results are consistent) which can cause a false low HbA1C.

From your readings, the things I would be most concerned about are your night time bathroom visits (which could be explained by many things) and your obsession with having diabetes despite the evidence otherwise.
I feel you should get to the bottom of this obsessive behaviour

 

[Lucyr]

I don't want to just worry, but because I have Low C-Petide too and my fasting BS has increased (via Glucometer) and is always higher than it should be now. Surely there's a reason for this and the low Fasting Insulin and Low C-Peptide, either my Pancreas or T1 / LADA, maybe not yet, LADA is more my concern

Your blood sugar and hba1c are normal so there’s no need to measure your cpeptide. Low cpeptide is only an issue when blood sugar is high.

 

[adz81]

However, 90% of us are very happy to rely on HbA1C because false lows are very rare.
Ok, we may also have symptoms of high blood sugars like thirst and tiredness and frequent toilet visits. Some may take finger prick readings which will be much much much higher than 5.4 - almost certainly double figures.

The most common reason for inaccuracies in HbA1C is anaemia. You don’t mention this although I suspect it was included in your blood tests.
Iron deficiency anaemia may cause a higher HbA1C whereas Hemolytic anaemia may cause a lower HbA1C.

Are you taking dapsone, sulfasalazine, ribavirin, and antiretroviral drugs or had a blood transfusion recently (and previously)? These are the only other things I found (apart from a mistake in your test which is very unlikely given your test results are consistent) which can cause a false low HbA1C.

From your readings, the things I would be most concerned about are your night time bathroom visits (which could be explained by many things) and your obsession with having diabetes despite the evidence otherwise.
I feel you should get to the bottom of this obsessive behaviour

I don't have anaemia, but I have Ferritin on the lower end of the range. This has been highlighted to me and from my own findings. I have had this for a couple of years and it doesn't increase much, despite my efforts.

I have never taken any of the things you've listed.

I have had a few HbA1C tests, in the past couple of years, with other tests. The highest it's been was 35 mmol.

 

[Inka]

HbA1c isn't always accurate. In some people it can read too low or too high. However, the reported HbA1c seems entirely consistent with the blood glucose readings (and the other tests) so I don't think there's any reason to disbelieve it. These are all things consistent with someone who doesn't have diabetes.

True but that’s rare and when someone clearly has unfounded anxiety about diabetes, I didn’t want to overcomplicate things or cause unnecessary anxiety.

 

[Inka]

I don't have anaemia, but I have Ferritin on the lower end of the range. This has been highlighted to me and from my own findings. I have had this for a couple of years and it doesn't increase much, despite my efforts.

I have never taken any of the things you've listed.

I have had a few HbA1C tests, in the past couple of years, with other tests. The highest it's been was 35 mmol.

So is my ferritin. However both myself and my consultant think my HbA1C is accurate and that that is not an issue.

 

[Bruce Stephens]

I have had a few HbA1C tests, in the past couple of years, with other tests. The highest it's been was 35 mmol.

And all your other tests look consistent with that.

 

[Inka]

I don't have anaemia, but I have Ferritin on the lower end of the range. This has been highlighted to me and from my own findings. I have had this for a couple of years and it doesn't increase much, despite my efforts.

I have never taken any of the things you've listed.

I have had a few HbA1C tests, in the past couple of years, with other tests. The highest it's been was 35 mmol.

Who did these tests, and is it the case that your GP did one or more of your HbA1C tests?

 

[adz81]

Who did these tests, and is it the case that your GP did one or more of your HbA1C tests?

A mix really. GP's and privately, similar results. Yes, the GP did a few of the HbA1c, the highest of 35mmol, was with them. All my results are pretty similar between both parties.

 

[dannybgoode]

A mix really. GP's and privately, similar results. Yes, the GP did a few of the HbA1c, the highest of 35mmol, was with them. All my results are pretty similar between both parties.

If you've had numerous readings done both via the GP and privately and they're all landing around the 34-35 mark then there is absolutely no need to have any other tests.

You're not diabetic. You're not prediabetic. You're smack bang in the 'normal' zone. So normal any other tests are just making the private clinic a bit extra towards their Christmas party fund.

 

[Inka]

A mix really. GP's and privately, similar results. Yes, the GP did a few of the HbA1c, the highest of 35mmol, was with them. All my results are pretty similar between both parties.

So clearly not diabetic then 🙂 Why are you having all these HbA1C tests? Presumably your GP explained that you weren’t diabetic so why have you gone on to have further tests?

Do you have Type 2 in your family, for example? Are you overweight?

 

[adz81]

If you've had numerous readings done both via the GP and privately and they're all landing around the 34-35 mark then there is absolutely no need to have any other tests.

You're not diabetic. You're not prediabetic. You're smack bang in the 'normal' zone. So normal any other tests are just making the private clinic a bit extra towards their Christmas party fund.

I wanted as many tests as I could, as i was peeing more than usual, at night, that's where my concerns started. My concerns remained when I had the 'extra' tests, as explained above.

 

[helli]

I wanted as many tests as I could, as i was peeing more than usual, at night, that's where my concerns started. My concerns remained when I had the 'extra' tests, as explained above.

And have you investigated anything else which may cause your extra peeing such as prostrate issues?
Diabetes is not the only condition which may cause this and all your test results point to diabetes not being the cause.
Have you tried drinking less in the evening?

 

[Lucyr]

I wanted as many tests as I could, as i was peeing more than usual, at night, that's where my concerns started. My concerns remained when I had the 'extra' tests, as explained above.

I think it would be better to spend your money treating your health anxiety.

All this stress isn’t good for your health

 

[Inka]

I wanted as many tests as I could, as i was peeing more than usual, at night, that's where my concerns started. My concerns remained when I had the 'extra' tests, as explained above.

Type 1/LADA would be one of the rarer reasons for peeing a lot at night, and you weren’t peeing that much anyway (compared with an undiagnosed Type 1). I was literally peeing every five minutes before I was diagnosed and producing almost a pint. It’s not normal urinary frequency, it’s unbelievable. More than that, I had excessive thirst and looked like a skeleton as the weight had dropped off me very, very quickly. My blood glucose was 30 and I was on the verge of DKA.

You really need to accept the results of those numerous normal HbA1Cs. If you can’t, or if you find yourself thinking “Well, I’ll just have some more tests…” then you’d be best seeking some help for your Health anxiety

 

[adz81]

So clearly not diabetic then 🙂 Why are you having all these HbA1C tests? Presumably your GP explained that you weren’t diabetic so why have you gone on to have further tests?

Do you have Type 2 in your family, for example? Are you overweight?

My 'love of tests' started a few months after peeing more at night and i was eating lots of carbs to Bulk up, higher carbs and peeing more, i was thinking T2, but not too concerned at that point. I'm naturally slim, although I've gained weight now due to my bulk and NO Diabetes in the family as far as I know.

So wanted to investigate as the GP's were not sure why, if it wasn't OA Bladder, which they doubted. So i felt lost. I thought, 'I will investigate myself then'. I have all my bloods done, some more than others. I wanted to have more HbA1c to see if things had changed, after 3 months (the time frame for HbA1c).

I didn't request numerous Hba1C's with the GP. They wanted to investigate as they were unsure, so they tested everything again. So, i ended up having a few HbA1c's in the space of 2 years or so. I don't have

 

[Inka]

And did the GP tell you that your HbA1C was normal?

Look for other causes of your urination. I think you said you’d had prostate tests, but there are other causes too.