Trulicity

Jenniw1990

Well-Known Member
Relationship to Diabetes
Type 2
Hi Everyone,
I am type 2, aged 30, weight 71kg and on 3 different meds. First diagnosed (2019) with 103mmol, my current AC1 is 66mmol. The meds dont seem to be working as well as we would hope.

What are peoples experiences with Trulicity? My DN has mentioned it to me but also said at the same time that my weight is a little too low for it (as i can cause weight loss)

What were some of the reasons your DN's suggested for you to be put on it, does it hurt and does it work?

Thanks in advance
Jenni :)
 
Are you sure that you are type 2?

A little young, not overweight, meds not working, could you be a slow on set type 1?
 
Are you sure that you are type 2?

A little young, not overweight, meds not working, could you be a slow on set type 1?
Well it's not something I had thought about being mis diagnosed? How do they determine if you are T1 or T2, do I just ask to be re tested?
 
Well it's not something I had thought about being mis diagnosed? How do they determine if you are T1 or T2, do I just ask to be re tested?
There are specific tests for Type 1, a C peptide test and also an antibody test. They take a bit longer than other tests to get results and the blood samples often have to be taken at the hospital as the samples need to be stored at a certain temperature. So you could ask about those.
 
There are specific tests for Type 1, a C peptide test and also an antibody test. They take a bit longer than other tests to get results and the blood samples often have to be taken at the hospital as the samples need to be stored at a certain temperature. So you could ask about those.
Thank you, I think I will call my DN tomorrow and have a chat with her, see if this is something that she may have thought about?
 
The first question to ask is "Why do you think that I am type 2?" It may be that the tests have already been done. The antibody test checks to see if your body is killing off the insulin producing cells, and the c-peptide tells how much insulin you are making.

Type 2s often make more than normal and type 1 too little. No medication given by mouth wiill work for type 1, although it may appear to do so, possibly due to the changes in diet.
 
I'm another one who suspects you might be a slow onset Type 1 or LADA (Latent Automimmune Diabetes in Adults).

Just to clarify the diabetes diagnosis situation..... An HbA1c result of 48 or more gets you a diagnosis of diabetes. After that clinical signs such as age, BMI (Body Mass Index) poor diet, disordered eating may point towards Type 2 but there is no specific test done and it is an assumption based on how you present. Many HCPS (Health Care Professionals) are under the misunderstanding that Type 1 only exhibits in children and young adults, so if you are over 20 you must be Type 2 in their eyes, so they treat you with Type 2 medication. This is further complicated by the fact that Type 1 diabetes in later life often has a slower onset, so it may appear to respond to Type 2 meds and/or lifestyle changes but gradually needs stronger medication. I am quite sure there are a good number of Type 2 diabetics on insulin who are actually Type 1 but have never been properly tested.

As stated above, the tests which should indicate if you are Type 1 are C-peptide (which measures the amount of insulin you are producing) and GAD antibody test which looks for the antibodies produced by the immune system which attack the insulin producing beta cells in the pancreas and kill them which is the cause of Type 1 diabetes.

As @leonS says, put them o the spot and ask them why they think you are Type 2 when you are not particularly overweight and relatively young and not responding to the routine Type 2 medication. Personally, I don't think they should be considering Trulicity before they have ruled out Type 1. You might have to push for a referral to a specialist diabetes clinic to get the appropriate testing done. Most diabetes nurses at GP practices have very limited training or knowledge of Type 1 diabetes and many GP are even less well informed, so you might need to be quite firm about asking for the tests and a referral. The tests mentioned can sometimes have results which are difficult to interpret which is why a consultant at a hospital clinic should be overseeing them and as stated one of them needs frozen within a very short space of time before being sent off to the lab in that state so most GP practices do not have the facilities for that or the onward transport of a frozen sample to an appropriate lab for testing and there are only a few in the country which do that testing, so again it needs to be handled by a department which have logistics in place for such sample storage and dispatch.

Sorry if that all sounds complicated but unfortunately with diabetes, you have to be your own expert and particularly with staff at GP practices, who often don't have enough knowledge, you have to do your homework and be prepared to fight your corner. Having the correct diagnosis is really important so that you get appropriate treatment, rather than them trying all sorts of drugs on you just in case they might work, because they have a blinkered approach to your diagnosis and haven't actually considered that you might be Type 1.
 
Further to the above, I was 56yrs old at diagnosis with Type 1 diabetes (initially assumed to be Type 2) and there are many more of us late starters here on the forum but probably the most high profile Type 1 diabetic who was diagnosed in later life was our previous Prime Minister Teresa May, so do be prepared to argue if they state that you can't be Type 1 because you are not a child.... this is a common misconception which is why it is important to be prepared with information to counter it. Good luck fighting your corner. Of course you may just be an unusual Type 2 and indeed there are other more exotic forms of diabetes than just Type 1 or Type 2 so a negative Type 1 testing result still doesn't necessarily indicate that you are Type 2.
 
Thanks for that insight @Inka

I think I would be wanting to know the numerical results of the C-peptide and GAD antibody tests and who assessed they were normal. The problem with LADA is that results can be inconclusive at times and it really should be a consultant who interprets them along with your other clinical presentation.

As regards your query about cravings for sweet stuff in your previous post, have you gained control of that or is it still a problem? I appreciate that it was a couple of years ago now. I was a sugar addict, chocaholic and bread and potato fiend pre diagnosis. Cutting out all the carb rich foods like bread and pasta and rice and most fruit as well as the obvious sweet stuff and eating more fat, helped me to gain control of my eating disorder, which is why I stick to eating low carb even though I could just inject insulin for those things now.
 
Agreed @rebrascora If the nurse was just passing on the consultant’s verdict then that’s fine, but if it was the diabetes ‘expert’ nurse diagnosing, I’d want to check.
 
@Jenniw1990 You said in an earlier thread that you’d had the Type 1 tests and it had been ruled out?:

Post in thread 'That time of month :('
http://forum.diabetes.org.uk/boards/threads/that-time-of-month.83746/post-932831

You mention your weight, but what’s your BMI?
Yes they did the initial test and just said to me i wasnt type 1 but type 2. As i didnt have a clue about anything at the time and the fact i was in total shock i obviously didnt question this and just agreed that i should go straight on to metformin and glimipiride to get my numbers from 103 down as quickly as possible. My bmi is 28, so only just over the 25 my GP says it should be??
 
Thanks for that insight @Inka

I think I would be wanting to know the numerical results of the C-peptide and GAD antibody tests and who assessed they were normal. The problem with LADA is that results can be inconclusive at times and it really should be a consultant who interprets them along with your other clinical presentation.

As regards your query about cravings for sweet stuff in your previous post, have you gained control of that or is it still a problem? I appreciate that it was a couple of years ago now. I was a sugar addict, chocaholic and bread and potato fiend pre diagnosis. Cutting out all the carb rich foods like bread and pasta and rice and most fruit as well as the obvious sweet stuff and eating more fat, helped me to gain control of my eating disorder, which is why I stick to eating low carb even though I could just inject insulin for those things now.
in regards to the sweet stuff, i am much better then i used to be, i am currently having telephone counselling about my emotional eating habits and that i heping because i am not hiding it anymore. i am more concious about what i am eating but sometimes it not as simple as that. i have started my food diary again so i can see what i am eating and not just eating for the sake of it and i cant record how i am feeling when the cravings happen. i just go through stages where for some weeks i am totally on the ball and theres not stopping me and then suddenly my mood changes and my motivation buggers off !!
 
Agreed @rebrascora If the nurse was just passing on the consultant’s verdict then that’s fine, but if it was the diabetes ‘expert’ nurse diagnosing, I’d want to check.
i am not entirely sure if i am being honest. I know the nurse i see is very knowledgable but i suppose that doesnt actually mean she is a specialist??
 
I'm another one who suspects you might be a slow onset Type 1 or LADA (Latent Automimmune Diabetes in Adults).

Just to clarify the diabetes diagnosis situation..... An HbA1c result of 48 or more gets you a diagnosis of diabetes. After that clinical signs such as age, BMI (Body Mass Index) poor diet, disordered eating may point towards Type 2 but there is no specific test done and it is an assumption based on how you present. Many HCPS (Health Care Professionals) are under the misunderstanding that Type 1 only exhibits in children and young adults, so if you are over 20 you must be Type 2 in their eyes, so they treat you with Type 2 medication. This is further complicated by the fact that Type 1 diabetes in later life often has a slower onset, so it may appear to respond to Type 2 meds and/or lifestyle changes but gradually needs stronger medication. I am quite sure there are a good number of Type 2 diabetics on insulin who are actually Type 1 but have never been properly tested.

As stated above, the tests which should indicate if you are Type 1 are C-peptide (which measures the amount of insulin you are producing) and GAD antibody test which looks for the antibodies produced by the immune system which attack the insulin producing beta cells in the pancreas and kill them which is the cause of Type 1 diabetes.

As @leonS says, put them o the spot and ask them why they think you are Type 2 when you are not particularly overweight and relatively young and not responding to the routine Type 2 medication. Personally, I don't think they should be considering Trulicity before they have ruled out Type 1. You might have to push for a referral to a specialist diabetes clinic to get the appropriate testing done. Most diabetes nurses at GP practices have very limited training or knowledge of Type 1 diabetes and many GP are even less well informed, so you might need to be quite firm about asking for the tests and a referral. The tests mentioned can sometimes have results which are difficult to interpret which is why a consultant at a hospital clinic should be overseeing them and as stated one of them needs frozen within a very short space of time before being sent off to the lab in that state so most GP practices do not have the facilities for that or the onward transport of a frozen sample to an appropriate lab for testing and there are only a few in the country which do that testing, so again it needs to be handled by a department which have logistics in place for such sample storage and dispatch.

Sorry if that all sounds complicated but unfortunately with diabetes, you have to be your own expert and particularly with staff at GP practices, who often don't have enough knowledge, you have to do your homework and be prepared to fight your corner. Having the correct diagnosis is really important so that you get appropriate treatment, rather than them trying all sorts of drugs on you just in case they might work, because they have a blinkered approach to your diagnosis and haven't actually considered that you might be Type 1.
No, thank you thats all amazing information for me to go ahead with :)
 
i am not entirely sure if i am being honest. I know the nurse i see is very knowledgable but i suppose that doesnt actually mean she is a specialist??

It doesn’t really matter if she’s a specialist nurse. It’s more a question of whether she was just telling you what the consultant had said about your test results or if she was interpreting them herself. I would guess she was just passing on the information but it would be sensible to check :)
 
So i have spoken to my DN this morning and she confirmed we did the GAD tests at diagnosis and that the numbers pointed in the direction of type 2. She believes that my body isnt responding to the 3 lots of medication that i am on now (we have chopped and changed to different ones as well) i am at 66mmol at the moment and my next AC1 test is in october. She said the next and only option left (according to guidlines when it comes to triple therapy) is insulin which i am terrified about and really dont want it. I dont want to offend anyone by saying this but i feel in myself that i have failed if i end up going on insulin....that and i am not a massive fan of having to inject! I have asked her to put me on the list to speak to a diabetic dietician (we had to hold of due to covid but they are starting up again)
 
So i have spoken to my DN this morning and she confirmed we did the GAD tests at diagnosis and that the numbers pointed in the direction of type 2. She believes that my body isnt responding to the 3 lots of medication that i am on now (we have chopped and changed to different ones as well) i am at 66mmol at the moment and my next AC1 test is in october. She said the next and only option left (according to guidlines when it comes to triple therapy) is insulin which i am terrified about and really dont want it. I dont want to offend anyone by saying this but i feel in myself that i have failed if i end up going on insulin....that and i am not a massive fan of having to inject! I have asked her to put me on the list to speak to a diabetic dietician (we had to hold of due to covid but they are starting up again)
Hi. You won't have failed if you need insulin. I am just above the C-Peptide level for T1 so still labelled as T2 and have been on insulin for several years. I have a low-carb diet and a good BMI so the current two tests don't show up all the causes of insulin deficiency. BTW be careful with dieticians as many haven't a clue.
 
Hi. You won't have failed if you need insulin. I am just above the C-Peptide level for T1 so still labelled as T2 and have been on insulin for several years. I have a low-carb diet and a good BMI so the current two tests don't show up all the causes of insulin deficiency. BTW be careful with dieticians as many haven't a clue.
This dietician is a specialist in diabetes management, so if i can get in with her (fingers crossed) hopefully there will be some benefits. How often do you have to inject?
 
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