Hello everyone.
Feel I should put my two-pennies worth in here, as a vet. Are there no other vets on this forum? Before I write anything I should state that for the last four and half years I have only worked with horses (and donkeys!), so am a bit out of touch with other animals.
It is amazing how different species have such different metabolisms and react to situations differently. The reason the dairy cows were being tested for ketones was to look for subclinical (no signs yet) ketosis. It is very very rare (never say never) for a cow to become diabetic and it is likely their blood glucose was pretty much normal. Dairy cows, producing a large amount of milk, have the metabolism of elite athletes and can easily fall into negative energy balance. Ketosis easily occurs in ruminants and can make the cow very sick - it will NOT be due to a lack of insulin NOR severe hyperglycaemia. Testing the cow for ketones, or more specifically beta-hydroxybutyrate, will alert the farmer to low levels of ketones, so that action can be taken before the animals become off their food and drop their milk production.
Pumper Sue, yes, many people can smell ketones, but not everyone can, and if the cow was in full blown ketosis ie sick, a lot of vets would not need to test the blood or milk as they would be able to smell the ketones. However many cows are tested for subclinical ketosis to alert a problem before it happens. The milk could have been tested, but usually its quicker, easier and more accurate to take a quick blood sample from the tail vein. I?ve just phoned a farm animal vet colleague who said that it costs less than ?4 a cow to take and test the blood. The amount a farmer would lose through lost milk production if clinical ketosis occurs would be a lot lot lot more!
There?s so much variation between species. Dogs, cats and chinchillas commonly get diabetes like in people, although there is much debate over type 1 vs type 2 in each individual animal. I agree Robster, you cannot aim to achieve the same type of control in pets and in my student days I saw of lot of blind dogs and cats from diabetic complications despite best efforts at treatment. Having said that I think you?re much more likely to get offered CGM for your dog than from the NHS!
My professional interest is horses and they NEVER become diabetic. However a lot of overweight native breeds (significant genetic component) have a very marked insulin resistance with
normall glucose levels. I have measured fasting insulin levels up to 20 times normal. These ponies nearly always go on to develop a horrible condition called laminitis, which affects the small blood vessels in their feet and is very painful. Treatment of the underlying insulin resistance is mainly diet and exercise, but metformin seems to help too, although some experts think that this poorly absorbed by the horse?s stomach. I hope other type 2 treatments are being studied in horses so that we can use them soon?
As another point to show how different species are, small fat ponies and donkeys NEVER produce ketones, but if restricted from food for over 24 hours will get loads of fat (triglycerides) in their blood (hyperlipaemia) which causes lots of problems including liver failure and usually kills them,
😱 unless aggressive and intensive treatment is undertaken. Bigger horses can happily be starved for days without this causing any problems.
Sorry if this post is a bit long and complicated, but this thread has certainly stirred up some interest so I thought I?d better put some veterinary input. The take home message is that you cannot extrapolate from one species to another - one of the reasons why the vet training is so long?
😎