Chemistry trick paves way for safer diabetes medication

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Northerner

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Type 1
New research from the University of Copenhagen points to an entirely new approach for designing insulin-based pharmaceuticals. The approach could open the door for more personalized medications with fewer side effects for Type 1 Diabetes patients.

Knud J. Jensen is a professor at the University of Copenhagen's Department of Chemistry. Together with Technical University of Denmark (DTU) and Novo Nordisk researchers, he has published "Construction of Insulin 18-mer Nanoassemblies Driven by Coordination to Iron (II) and Zink (II) Ions at Distinct Sites" in the renowned journal, Angewandte Chemie.

"We have discovered an entirely new method of modifying a molecule - Insulin - that is important for 35 million diabetes patients. We are incredibly happy with that," says Professor Jensen.

http://www.eurekalert.org/pub_releases/2016-02/fos--ctp021816.php

Hmm...perhaps someone should tell them that, actually, basal rates aren't uniform throughout the day, hence the facility to tune them by the hour on pumps... 🙄
 
Well yes, basal rates do vary, but ( short of everyone getting a pump) it's probably easier to manage the variations with an insulin that you know is going to be stable rather than one that claims to be but has peaks and troughs just where you don't need them ( Yes, Lantus, I'm talking to you)
 
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