insulin

  1. Northerner

    How the insulin receptor works

    As we are approaching the 100th anniversary of the discovery of insulin, a wide array of its signaling pathways has been defined. However, the initial step in insulin action, i.e. the engagement with its cell-surface receptor and the resulting conformational change, which propagates across the...
  2. Northerner

    Some viruses produce insulin-like hormones that can stimulate human cells

    Every cell in your body responds to the hormone insulin, and if that process starts to fail, you get diabetes. In an unexpected finding, scientists at Joslin Diabetes Center have identified four viruses that can produce insulin-like hormones that are active on human cells. The discovery brings...
  3. Northerner

    Tiny drug-delivering capsules could sustain transplanted insulin-producing cells

    A drug-carrying microsphere within a cell-bearing microcapsule could be the key to transplanting insulin-secreting pig pancreas cells into human patients whose own cells have been destroyed by type I diabetes. In a new in vitro study by University of Illinois engineers, the insulin-secreting...
  4. Northerner

    Is the Public’s Lack of Empathy to Blame for Increased Insulin Costs? (USA)

    How exactly did insulin become unaffordable? This is the question that Drew Pendergrass explores in a widely read piece for Harvard Political Review, which was published on January 22, 2018. Pendergrass begins by telling the story of Alec Raeshawn Smith, who recently died after an all-too-common...
  5. R

    Recruiting research participants with Type 1 diabetes

    Have you been diagnosed with Type 1 Diabetes? If so, and if you meet the criteria below, we would like to invite you to take part in a research study that is being carried out at the University of East Anglia. The research will involve completing online, anonymous questionnaires that should...
  6. R

    Extended travel to Malawi

    Hi, I'm hoping someone can help me. I'm going to moving to live in Malawi for a year to do research work. Does anyone know how I can source my insulin out there? I'm about to move onto a new pump with prefilled catridges. Will i be able to get a whole year's supply? Many thanks in advance...
  7. Northerner

    Injection alternative: Model predicts performance of glucose-responsive insulin

    People with Type 1 diabetes must check their blood glucose several times a day and inject themselves with insulin to keep their blood sugar levels within a healthy range. A better alternative, long sought by diabetes researchers, would be insulin that is engineered to linger in the bloodstream...
  8. Northerner

    New oral diabetes drug shows promise in phase 3 trial for patients with type 1 diabetes

    A University of Colorado Anschutz Medical Campus study finds sotagliflozin helps control glucose and reduces the need for insulin in patients with type 1 diabetes. Principal results were published in the New England Journal of Medicine of a global Phase 3 clinical trial in patients with type 1...
  9. Northerner

    Insulin therapy initially declined and delayed by an average of two years

    Although delaying insulin therapy leads to a worsening progression of diabetes, new research by Brigham and Women's Hospital has found 30 percent of type 2 diabetic patients don't begin insulin, a medication used to lower the body's blood sugar levels, when it's initially recommended, with the...
  10. Northerner

    Diabetics in need of insulin, donation efforts underway

    Being prepared for a hurricane like Harvey means having a plan to leave, packing essentials like food, water, and batteries. However, there is a large segment of the community that needs other lifesaving supplies. "There's a lot of elderly, there's a lot of fixed income, and there's a lot of...
  11. Northerner

    New measure of insulin-making cells could gauge diabetes progression, treatment

    Researchers at the University of Wisconsin-Madison have developed a new measurement for the volume and activity of beta cells, the source of the sugar-regulating hormone insulin. In a study published in the August edition of the journal Diabetes, Weibo Cai and colleagues used a PET scanner to...
  12. D

    Buying insulin in Bangkok

    Hi there, I'm flying to Vietnam in January to start a 3-4 month trip backpacking around SE Asia before flying on to Australia. I use Levemir and NovoRapid and I'm planning on taking as much insulin I can carry in Frio bags however I think I will need to purchase more before I make it to...
  13. Amity Island

    Basal dose short at moment....

    Hi Everyone, I'm really appreciating all the help from the members on here since I joined a few days ago. I just started Tresiba a week go, so my basal dose is currently short at the moment, i'm having to add an extra 4u of humalog every 6hrs to keep blood sugars safe. Does anybody know how...
  14. Amity Island

    So confused.......about tresiba.

    Evening Everyone, Can anybody give me a definitive answer to my question, i've tried the "experts" the local NHS diabetes specialists but they don't understand my question, let alone answer it. Here we go. 1. TRESIBA lasts for 48hrs, it's not adjustable on a daily basis, takes three days to...
  15. S

    Tiredness...Help Please

    Hello! I have been Diabetic for over 12 years now and my sugar control has dramatically improved since going on an insulin pump last year. This is great and I thought it would reduce my daily tiredness battle.... but it hasn't and I feel lethargic throughout the day on a regular basis. I have...
  16. Northerner

    Basal-Bolus Versus Once, Twice, and Even Three Times A Day of Long-Acting Insulin (Type 2)

    Satoru Tsujii, MD, PhD, of the department of endocrinology at Tenri Hospital in Japan, and colleagues evaluated data from the Diabetes Distress and Care Registry on 757 adults (mean age, 65.7 years) with type 2 diabetes (mean HbA1c level, 7.8%; mean duration of insulin therapy, 11.3 years) who...
  17. Steve Liddle

    Insulin storage temperatures ?

    Recently came across an article from the good housekeeping guide or something about the best place to store raw meat, cooked meat, dairy and the like. Re-arranged the fridge and put the vegetables where the insulin was stored at the bottom of the fridge. Noticed frozen carrots and hence the...
  18. Stefan Diabetes UK

    Diabetes care in hospital: your thoughts?

    MPs are getting started on an inquiry in to diabetes care in hospital, and are looking for anyone with experience, good or bad, to share their comments. We know these reports come out much better if people living with diabetes are involved from the start, so if you have a minute to give your...
  19. Rachel Tait

    Getting insulin abroad HELP!

    Hi there, I am planning a trip to the USA in September for 3 months and have a dilemma I'm hoping someone can help me with. I will be cycling (eek! it's a super long way) from Florida to California over 3 months. I won't have constant fridge access and won't be able to bring 3 months worth of...
  20. Northerner

    A sustained and controllable insulin release system

    Researchers have developed an insulin release system with sustained and controllable delivery. The system combines two original technologies, SPRA and PPRX, which provide complimentary benefits for insulin delivery. https://www.sciencedaily.com/releases/2017/02/170227100744.htm If someone...
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