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Toujeo

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This thread is now closed. Please contact Anna DUK, Ieva DUK or everydayupsanddowns if you would like it re-opened.

Annette Arundell

Active Member
Relationship to Diabetes
Type 1
Hi I'm going into hospital hopefully tomorrow as so many diabetes problems, ive already posted im on Abasaglar, its not working for me, so I thought of maybe asking about toujeo as its once a day, as I can't go on like this, as I said before I was on levemir but that didn't last, even with 2 shots, then Abasaglar which I'm on now, and its peaks after 6 hours and makes levels low, at night , as on 2 shots, and one shot wouldn't last 24 hrs, anyone know about toujeo, it says flat profile, thats what I need, as no matter how I try i can't get dose and timing right with Abasaglar, I'm either high or low, nothing in between, I was on tresiba for short time, but made me very unwell can anyone give me there views on this, thank you lovely people.
 
@Michael12421 is using Toujeo but not by choice I believe and would probably swap back to Lantus given the opportunity.

How do you know that you need a flat insulin profile and it is not your insulin needs which are dipping in the middle of the night and then rising in the morning, as that is a more common situation. Few people need the same amount of basal insulin throughout the day and night.
Tresiba is as flat a profile as any basal insulin and you have already tried that

I don't understand what you are saying about Levemir split dose not lasting?..... it lasts a minimum of 16-17 hours I believe so the 2 doses are always overlapping and don't run out before the next starts. I wonder if you just didn't have the right balance of doses and timing. It takes quite a bit of tweaking to find the correct doses and even when you do it often needs adjusting... at least it does for me, taking into account the weather and activity levels etc. And then I still need to inject quick acting insulin as soon as I wake up in the morning to deal with DP/FOTF.
 
@Michael12421 is using Toujeo but not by choice I believe and would probably swap back to Lantus given the opportunity.

How do you know that you need a flat insulin profile and it is not your insulin needs which are dipping in the middle of the night and then rising in the morning, as that is a more common situation. Few people need the same amount of basal insulin throughout the day and night.
Tresiba is as flat a profile as any basal insulin and you have already tried that

I don't understand what you are saying about Levemir split dose not lasting?..... it lasts a minimum of 16-17 hours I believe so the 2 doses are always overlapping and don't run out before the next starts. I wonder if you just didn't have the right balance of doses and timing. It takes quite a bit of tweaking to find the correct doses and even when you do it often needs adjusting... at least it does for me, taking into account the weather and activity levels etc. And then I still need to inject quick acting insulin as soon as I wake up in the morning to deal with DP/FOTF.
As a matter of interest, if you are not getting a flat line during fasting periods, how do you know when your basal amount is correct?
 
I rarely get flat horizontal lines on my graph, even when fasting. The best I can hope for is that the correct dose will keep me within range without needing corrections of QA insulin or carbs over the 12 hour period most of the time.

You can usually see it without fasting as the shape of my Libre graph changes from a baseline with spikes to running along the top of my range with dips where I am making corrections to stay in range but then usually starts to drift up again.
If my Levemir dose is as close as I can get it to being right during the day it will keep me in range in the morning with a little help from some QA but may drop me a little low in the afternoon/evening so I know I may need a top up.

If I am into regular daily exercise I can sometimes get away with no insulin at night and still hypo around 4am when my daytime Levemir has pretty well run out of steam (I take it at 7am). It is a constant balancing act for me. Each night I assess how much exercise I did that day and the previous days, when I ate, how much protein I had and my bedtime reading before deciding how much evening Levemir I am likely to need. All that said, I would fight tooth and nail to keep my Levemir because short of an insulin pump, it allows me to adjust it to what my body needs. I think some people are quite lucky to get a flat line on their graph with basal testing and it may well be that these are the people who benefit from the likes of Tresiba. Most people I guess, it will be a question of best fit as regards basal dose rather than achieving a straight line. Just keeping things mostly within range with their basal is the best that they can do.
 
@Michael12421 is using Toujeo but not by choice I believe and would probably swap back to Lantus given the opportunity.

How do you know that you need a flat insulin profile and it is not your insulin needs which are dipping in the middle of the night and then rising in the morning, as that is a more common situation. Few people need the same amount of basal insulin throughout the day and night.
Tresiba is as flat a profile as any basal insulin and you have already tried that

I don't understand what you are saying about Levemir split dose not lasting?..... it lasts a minimum of 16-17 hours I believe so the 2 doses are always overlapping and don't run out before the next starts. I wonder if you just didn't have the right balance of doses and timing. It takes quite a bit of tweaking to find the correct doses and even when you do it often needs adjusting... at least it does for me, taking into account the weather and activity levels etc. And then I still need to inject quick acting insulin as soon as I wake up in the morning to deal with DP/FOTF.
 
I rarely get flat horizontal lines on my graph, even when fasting. The best I can hope for is that the correct dose will keep me within range without needing corrections of QA insulin or carbs over the 12 hour period most of the time.

You can usually see it without fasting as the shape of my Libre graph changes from a baseline with spikes to running along the top of my range with dips where I am making corrections to stay in range but then usually starts to drift up again.
If my Levemir dose is as close as I can get it to being right during the day it will keep me in range in the morning with a little help from some QA but may drop me a little low in the afternoon/evening so I know I may need a top up.

If I am into regular daily exercise I can sometimes get away with no insulin at night and still hypo around 4am when my daytime Levemir has pretty well run out of steam (I take it at 7am). It is a constant balancing act for me. Each night I assess how much exercise I did that day and the previous days, when I ate, how much protein I had and my bedtime reading before deciding how much evening Levemir I am likely to need. All that said, I would fight tooth and nail to keep my Levemir because short of an insulin pump, it allows me to adjust it to what my body needs. I think some people are quite lucky to get a flat line on their graph with basal testing and it may well be that these are the people who benefit from the likes of Tresiba. Most people I guess, it will be a question of best fit as regards basal dose rather than achieving a straight line. Just keeping things mostly within range with their basal is the best that they can do.
Hi I'm not looking for flat profile, just don't want hypo through night and rise in morning on getting up.When I took levemir it didn't last 12 hrs with smaller doses I took 10 am and had to cut to 7 at night, but I started rising high before I started 2nd dose , then keep going higher on rising after taking small dose at night, this all started after I had covid in December, now on Abasaglar and it peaks after few hours in day, which is managable, with lows, but also peaks in early hours causing hypo , then on rising i go into the teens before breakfast, so now in hospital as diabetes out of control.

day
 
@Annette Arundell the highs and lows may be due to your body's insulin requirements rather than the insulin profile. If this is the case, you should be a candidate for an insulin pump which will allow you to alter your basal pattern throughout the day by pumping fast acting insulin at different rates rather than relying upon the profile of long acting insulins.
Has a pump been discussed with you? In your position, I think I would be pushing for one. It has made a huge difference to my ability to manage my varied insulin needs throughout the day.
 
I have been on Tujeo for more than a year (previously Lantus) and am very happy with it. It is 3 times stronger so you inject less, although the pen is adjusted so you dial the same number of units. Since being on Libre and seeing my overnight BG graph have managed to reduce 58 to 32 units to produce a flat sleeping curve. Also on Novorapid.
 
We have had a few members on Toujeo over the years. @Ivostas66 was one I think.

There are a few threads here, with some different experiences, some liking it, and others not so much.

When I was moved onto the basal/ bolus regime a couple of months after diagnosis, I met the most qualified DSN at the local diabetes centre, who been involved in a national study/ research into different types of basal insulin. She was adamant that Toujeo was the best basal for me, but warned that my GP would definitely question it due to its price (she said it was considerably more expensive than others as at the time it was one of the newest to market and also earning rave reviews). My GP contacted her and questioned why I was being put onto Toujeo, claiming it was really strong and would be difficult for me to control during the honeymoon period. However, she explained that as a teacher, with a young daughter, I needed to be on the 'most stable and reliable' (her words) basal. He then queried the cost with her and she stood her ground.

I have never had a problem with Toujeo. I inject 8 - 10 units each morning (depending on the time of year) and have found it to be stable and no side effects. Bolus is a different story completely though!!
 
Status
This thread is now closed. Please contact Anna DUK, Ieva DUK or everydayupsanddowns if you would like it re-opened.
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