Switching from Insulin to Metformin/Linagliptin

[Mom of Type 1]

Hi, need advice..

In my previous threads some time ago, my kid was diagnosed with Type1, however, auto immune test was negative but c-peptide was very low almost to none. His hba1c is 6.2 with insulin ( past 9 months, hba1c was stable at 6.1 or 6.2) . Now the doctor is recommending to switch to oral medication. Anyone experience this ?

 

[Lucyr]

Now the doctor is recommending to switch to oral medication. Anyone experience this ?

Ask for the cpeptide test results showing kid makes enough insulin of his own

 

[Mom of Type 1]

C-peptide super low, almost to none...should we give it a try on the oral medication ? Doctor also gave linagliptin which is supposed to make the pancreas create insulin..

 

[Lucyr]

C-peptide super low, almost to none...should we give it a try on the oral medication ? Doctor also gave linagliptin which is supposed to make the pancreas create insulin..

You have to already be making insulin for these tablets to be able to stimulate your pancreas to make more

 

[Inka]

C-peptide super low, almost to none...should we give it a try on the oral medication ? Doctor also gave linagliptin which is supposed to make the pancreas create insulin..

I think you’re in Malaysia? Google suggests that Type 2 is becoming more common in younger people (I can’t remember how old your child, but I think they’re a young adult?), but if your child has a very low C Peptide, then it’s very possible they might need insulin even if they are Type 2.

I’d ask for the actual number for the C Peptide test first, then ask the doctor to comment on the C Peptide value and what it means for your child now in their ability to control their blood sugar and in future.

 

[everydayupsanddowns]

This sounds very unusual @Mom of Type 1

CPeptide is something the body makes alongside insulin. But it isn’t included in man-made insulins.

So measuring cPep gives an idea of how much insulin the body can produce.

If your son’s cPeptide is very low it would seem to confirm T1 to me. His beta cells would have been destroyed by autoimmune attack and he would have little or no insulin production.

Oral meds often work by stimulating more insulin release - but you have to have functioning beta cells for them to work.

T2 is more often characterised by very high levels of natural insulin production, but that it doesn’t work properly (insulin resistance).

 

[Mom of Type 1]

Yeah, thats what I understand too..but doctor said give it a try...gave us medi for 2 weeks first....and if sugar level too high, ask to inject insulin...for starting to see whether it stabilizes....