Subcutaneous insulin therapy fails to protect against oxidative stress and inflammation

[Northerner]

Today, the gold standard for insulin therapy is the subcutaneous injection of insulin (CSII), despite a non-physiological route of administration with suboptimal glycemic control showed in some patients. Inability of CSII therapy to prevent inflammation and oxidative stress was firstly demonstrated in vivo on treated-diabetic rats, presenting a high variability of glycogen storage associated with glycemic fluctuations. This study suggests that targeting oxidative stress and/or inflammation could help the therapeutic management of diabetic patients.

https://www.sciencedaily.com/releases/2016/02/160229182551.htm

 

[Annette]

What this appears to say is that insulin injections don't help (T1s) because they cause other problems in some people (read: rats). Might I point out that without the insulin injections, the other problems wouldn't arise because we'd all be dead?🙄