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Newbie Question : A third drug!

PMA

New Member
Relationship to Diabetes
Type 2
Hi Everyone

It's good to know there is a place like this to ask questions and I hope someone can shed some light 🙂

I was diagnosed T2 some years ago and, after not seeing great results after Metformin alone, I eventually ended up on Metformin 1000mg twice a day and Sitagliptin 100mg once a day. My doctor introduced Rybelsus (3mg) as a third medication the other day because my HbA1c is still not good (74 in March 2025; it was 91 last July and 98 at some point before that).
  • Does anyone else have this combination of drugs and how have you found it?
  • What sort of results have you seen altogether?
  • Did you need to go up to 7mg of Rybelsus or was 3mg enough, taking into account the Metformin and Rybelsus as well?
  • Final question! Has the Rybelsus at 3mg had any impact on weight loss with this combination given that it's a semaglutide? I'm aware that semaglutides can impact appetite and so on.
The pharmacist has said today that the three drugs are sometimes prescribed together and the 3mg may be enough to reduce HbA1c levels, depending on my next blood test.

Many thanks
P
 
I'm afraid I can't help with the medication as I don't need any for diabetes - but, being nosey - do you check your blood glucose after eating?
What sort of numbers do you see - and what would you eat on a typical day?
I'm just curious looking at your increasing HbA1c levels despite the medication.
 
I'm afraid I can't help with the medication as I don't need any for diabetes - but, being nosey - do you check your blood glucose after eating?
What sort of numbers do you see - and what would you eat on a typical day?
I'm just curious looking at your increasing HbA1c levels despite the medication.
Hi Drummer
Thank you for your reply. I think my problem is when I eat, rather than what I eat. I work in mental health, often responding to crisis situations, which means my days can be irregular but I put my foot down at work in December 2024 and that appears to have had an impact, going down to 74 but my GP wants things to improve more by my next blood test in 3 months and I have to agree because I have been feeling quite unwell with it all in terms of diabetic symptoms and consequences. I'm changing jobs so that's going to have an impact too, I hope!
 
When you eat may have some impact but not as much as what you eat, all carbohydrates convert to glucose regardless of when you eat them though some people find they are less tolerant of carbs in the morning.
Do you do shift work or it is the time to eat proper meals that is a problem.
 
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