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lost 5kg but hba1c the same

Sounds like your recent dietary changes are proving effective. I wonder what would happen to your BG if you mislaid your tablets for a day or two. It might show Eddy Edson's guess is right.
 
JITR said:
Sounds like your recent dietary changes are proving effective. I wonder what would happen to your BG if you mislaid your tablets for a day or two. It might show Eddy Edson's guess is right.
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It could be so, but I guess I might need to stop for a month to let it get out of my system, I'm content to wait until my next hba1c, take small steps. I don't think you get much side effects on a low dose, I read it's over 1500mg taken for several years that is more likely to cause b12 deficiency.
 
MarcR said:
The consultant said it has some protective benefits, I've read it can prevent cancer and cardiovascular disease.
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Again just FWIW, I think the evidence for any of these benefits is pretty thin (unlike the case for SGLT2i's, semaglutide, tirzepatide where RCTs have delivered strong evidence for cardio-renal & a range of other benefits).

But met risks (including B12 deficiency) are very low so IMO anyway no harm in continuing with it.
 
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Most post meal was 8.1mmol/L so not as good, strange my fasting has fallen but my post meal has risen. 5.2 and 7.4 to 4.2 and 8.1 ?
 
MarcR said:
It could be so, but I guess I might need to stop for a month to let it get out of my system, I'm content to wait until my next hba1c, take small steps. I don't think you get much side effects on a low dose, I read it's over 1500mg taken for several years that is more likely to cause b12 deficiency.
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Absolutely correct. I would not advise anyone to make any changes to their medication without discussing with their medical team first.

I discussed my T2D diagnosis with my GP the day before my fatty liver diagnosis. The GP said NICE guidelines are to take Metformin, the specialist said 'treat it with diet'.

Prof Taylor's team at Newcastle University had shown losing 15 kg or more on a low calorie diet without medication (risk of hypos) would eliminate excess liver fat and, in many cases, put T2D into remission. I chose diet without medication.
 
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MarcR said:
Most post meal was 8.1mmol/L so not as good, strange my fasting has fallen but my post meal has risen. 5.2 and 7.4 to 4.2 and 8.1 ?
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Squidgy biology + variability in the fingerprick test => the difference in those numbers isn't very meaningful.
 
Eddy Edson said:
Squidgy biology + variability in the fingerprick test => the difference in those numbers isn't very meaningful.
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It's getting more mysterious, 2h after lunch I tested my blood and it was 4.4mmol/l. I'm guessing it's because I eat a lot more carbs for breakfast and hardly any for lunch. At breakfast a bid bowl of muesli, a banana, tangerine and apple and lots of raisins, whereas at lunch only one slice of wholemeal bread on the carb side.
 
MarcR said:
It's getting more mysterious, 2h after lunch I tested my blood and it was 4.4mmol/l. I'm guessing it's because I eat a lot more carbs for breakfast and hardly any for lunch. At breakfast a bid bowl of muesli, a banana, tangerine and apple and lots of raisins, whereas at lunch only one slice of wholemeal bread on the carb side.
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That breakfast would be at least a week's worth of carbs for me - I eat apple and raisins once a year - at Christmas. Not had a banana in over 8 years.
It gives you a lot of things not to eat if your levels require adjustment though.
 
I realised I'm not balancing my carbs, about 127g for breakfast and 13g dinner. I worked out of I halve the amount of alpen, have the banana for lunch, only add dried cranberries rather than raisins it works out to approx 60g for breakfast and 40g for dinner
 
MarcR said:
I realised I'm not balancing my carbs, about 127g for breakfast and 13g dinner. I worked out of I halve the amount of alpen, have the banana for lunch, only add dried cranberries rather than raisins it works out to approx 60g for breakfast and 40g for dinner
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Do you have a home testing monitor so you can check what effect your higher carb meal is having as if it is resulting in more than a 2-3mmol/l increase after 2 hours it would be better to even your carbs out.
I tended to look upon the carbs per day as being more like an amount per meal that kept my 2 hour post meal to less than 8mmol/l.
 
Leadinglights said:
Do you have a home testing monitor so you can check what effect your higher carb meal is having as if it is resulting in more than a 2-3mmol/l increase after 2 hours it would be better to even your carbs out.
I tended to look upon the carbs per day as being more like an amount per meal that kept my 2 hour post meal to less than 8mmol/l.
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I have a BG test device, I don't use it very often. Today I'm trying cutting out the extra raisins and reducing the alpen from 75g to 45g, if it doesn't work might have to have the banana for lunch instead.
 
Does anyone know how long Metformin affects blood glucose after you stop taking it? The Doctor told me it can take up to 3 months to see the full effect, but I'm wondering if you stop how long until it's effect is completely gone?
 
JITR said:
Simple answer: Metformin has an elimination half-life of approximately 17.6 hours. It takes approximately 5.5 x elimination half-life for a medicine to be cleared from your body which is 5.5 x 17.6 hours = 96.8 hours for metformin.
See https://www.drugs.com/pro/metformin.html
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I saw something like that but if it's takes 3 months to get the full effect, could it take 3 months to fully wear off?
 
I was thinking that dried cranberries are better than raisins but now I read they have added sugar so may be worse!
 
MarcR said:
I saw something like that but if it's takes 3 months to get the full effect, could it take 3 months to fully wear off?
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After a week (officially 5.5 days) residual Metformin will be too low to affect your BG levels.

For all I know other effects of Metformin, such as those on the Mitochondria, may persist for weeks and months.
 
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