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Invited to a study

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Grogg1

Grogg1

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Type 2
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I had a letter today to invite me to find out more about joining a diabetes study. The letter says it involves taking one extra tablet a day alongside my medication (metformin 500mg 1 a day).

I am going to respond to find out more but just wondered if anyone else had any idea what the study is and what the extra tablet could be.
 
Well done you for being part of research. I know from various places how difficult it can be to recruit people into studies, so it's great that you are doing this (whatever it is!)
 
Just don't say yes until you've satisfied yourself about the trial drug. They are unlikely give you the tradename of it but they do have to tell you what type it is - so they might say eg 'a GLP inhibitor' rather than eg 'Byetta' (if that is one of those)

So do your homework before agreeing or declining.

Years ago I was offered one such, a trial where women of a certain age could take a lower dose of a drug used in osteoporosis to see if it then prevented them getting osteoporosis. No undue side effects it said.

That's very odd, cos I trawled an osteoporosis forum - yes some of them did need the drug BUT it's side effects, if you got them and of course you might be lucky and not get them, were severe.

My sister - at the time actually dying of metastased cancer now virtually everywhere including her spine - was taking it alongside everything else including chemo - told me even those who HAD to take it like her, didn't want to and not to touch it with a bargepole when there was nowt (in that context) wrong with me. If I hadn't said I wanted to think about it and come home and Googled it - I'd have thought it sounded quite a reasonable idea.
 
Grogg1 said:
I had a letter today to invite me to find out more about joining a diabetes study. The letter says it involves taking one extra tablet a day alongside my medication (metformin 500mg 1 a day).

I am going to respond to find out more but just wondered if anyone else had any idea what the study is and what the extra tablet could be.
Click to expand...
Who sent the letter?
 
Northerner said:
Who sent the letter?
Click to expand...
It's come from my GP and it's called DECIDE STUDY. I did some googling today and if it's the same this is it:

"DECIDE is a pioneering real-world pragmatic trial investigating the effectiveness of dapagliflozin compared to Standard of Care for second line treatment

TBH I'm not keen to add a drug when at the moment I'm controlling my diabetes fairly well. Three years ago I was treated for breast cancer and I'm keen not to overly poison my body with drugs that I might not need. I'm going to go along for a chat but ATM I'm not keen to sign up. There was another study advertised at my hospital when I went for a blood test but as I was diagnosed over 12 months ago I wasn't eligible.

I'm happy to provide data for studies but not so keen to be a guinea pig for testing drugs. I know someone has to be brave enough to go to human trials but I'm not sure it's for me.

https://www.birmingham.ac.uk/Documents/college-mds/research/crnwm/DECIDE-Flyer.pdf
 
Grogg1 said:
I'm happy to provide data for studies but not so keen to be a guinea pig for testing drugs. I know someone has to be brave enough to go to human trials but I'm not sure it's for me.
Click to expand...
I think I would feel the same @Grogg1 🙂 If your diabetes is well-controlled then what might happen if you add a drug intended to lower your levels? The 'flozin' meds, as far as I know, work by making you pee more glucose out and can potentially lead to more UTIs.
 
Northerner said:
I think I would feel the same @Grogg1 🙂 If your diabetes is well-controlled then what might happen if you add a drug intended to lower your levels? The 'flozin' meds, as far as I know, work by making you pee more glucose out and can potentially lead to more UTIs.
Click to expand...

I really don't need anything that increases my peeing!! I'm top peer in this house, especially at night as I'm an awful sleeper. I've been the same since a child and I know it's mainly psychological as if I'm not thinking about it I can go hours e.g. busy in work and won't go from morning shower at 7am till 12pm but if I'm going to a meeting and think I should go just in case I'll be desperate again within an hour!!!
 
There is quite a bit going on with the "flozin" meds, and one I heard of recently was investigating why some patients taking these meds don't lose as much weight as expected.

Of course, it is critical that anyone participating in a trial is content to commit to it, as there will almost certainly be rerequirrements, if in nothing else, the feedback loop.

I do a lot of work with the NIHR, and some of the studies are absolutely fascinating, and some I'd need to be "in the loo" when they're recruiting.

Bearing in mind my current status, with it's almost 4 years standing, I rarely see anything I would qualify for, never mind, qualify and be accepted for.

Good luck whatever you decide. Lots of these studies are tricky to recruit for, but that doesn't mean it's right for you, or you should feel obliged t give it a go.

Long may your BC remission continue.
 
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