Insulin receptor and gene expression

[Northerner]

The discovery of insulin in the 1920s marked the breakthrough in the almost 3,500-year-long mystery of diabetes, a disease first described in ancient Egyptian papyruses. Until its discovery, physicians struggled to explain how symptoms such as sugary urine, constant thirst and frequent urination could lead to ailments ranging from blindness and nerve damage to coma and death.

Over the past century, scientists have detailed the hormone's central role as a regulator of blood sugar, mapped its cell-signaling pathways and established its involvement in diabetes and a staggering array of other chronic conditions, including neurodegeneration, cardiovascular disease and cancer.

https://www.sciencedaily.com/releases/2019/04/190404143631.htm

 

[trophywench]

At first I found the fact that insulin treatment of T1 was so young that 50 years previously I'd be lucky to still be alive by the time in my diabetes journey I actually took in the fact that it wasn't available in the UK until sometime in1923 although the 'purified but not commercially gone into large scale production' was available around Toronto in 1922.

However, later, it cheered me up that the fact that it was and still is so young must mean that further breakthroughs can and will happen even if they don't help me directly cos I'll be ashes by then.

I LOVE the Mayo Institute - and another great example of what sounds like really useful research. (And dislike intensely actuarial tables!)