Hi
@Alison Carr Some people find their body adjusts to taking Metformin SR when it is taken with food, others have no alternative but to give it up.
Unfortunately all the drugs for Type 2 diabetes have possible nasty side effects.
Gliclazide is a common one, it encourages (some say 'forces' ) the Beta cells to produce more insulin . Apart from the same possible side effects as Metformin there are constipation, High Blood Pressure, Hypoglycemia and it may also make the the beta cells 'burn out' quicker since in a Type 2 they're already making much more insulin than in a normal person.
SGLT2 Inhibitors definitely make you pee more often and the pee is high sugar possibly creating urinary tract and yeast infections. but they tend to cause low blood pressure rather than high. They also come with a small risk of some very nasty side effects.
Victoza has the same common side effects as SGLT2's except they swap the peeing for possible dizziness, blurred vison, mood changes and slurred speech. It is injected.
The next main drug is then insulin which is also injected and needs a dose appropriate for what you will eat (it's too slow acting to help much with what you have already eaten.
In my opinion, for those who can take it, the best Type 2 medicine is food - low carb food which has remission rate (without drugs) of around 50% (in those who can keep doing it). Alternative food based treatments are prolonged fasting or gastric surgery (if substantially overweight) or a short term a very low calorie diet such as the 'Newcastle diet. None of these are cures because you can still sabotage them (even gastric surgery) by eating too much of the wrong things after the memory of initial benefit has faded a little.