Glucose needs drop during high-intensity exercise in type 1 diabetes

[Northerner]

In patients with type 1 diabetes, glucose amounts necessary to maintain euglycemia during an exercise session follow an inverted U-shaped trajectory, with no external glucose needed at high-intensity exercise, according to recent findings.

Vinutha B. Shetty, MD, FRACP, a pediatric endocrinologist at Princess Margaret Hospital for Children in Perth, Australia, and colleagues evaluated nine patients with type 1 diabetes (six women; aged 14.6-25 years; mean age, 21.5 years) to determine the association between exercise intensity and glucose needs. Participants underwent euglycemic clamp with the initial insulin infusion rate set at the participant’s lowest basal insulin rate for those on an insulin pump, or at the dose of the long-acting insulin for those on multiple daily injections. Insulin rate was then modified to a level at which no exogenous glucose was required to sustain a stable level of 5 mmol/L to 6 mmol/L.

http://www.healio.com/endocrinology...ng-high-intensity-exercise-in-type-1-diabetes

 

[Matt Cycle]

Interesting (after trying to negotiate the scientific speak). I've no idea what my O2 peak is (I'm assuming this is the same as VO2 max that's always mentioned) so couldn't tell if my exercise intensity is low, high or whatever only from what I feel. It's not a large study group though and the results vary between people and exercise intensity. Guess it's trial and error and keep testing.

 

[Northerner]

Strikes me that it arrives at no useful conclusions whatsoever! 🙄

 

[HOBIE]

Just shows how good pumps are ! Doing tests like this a few year ago would have been very hard 😎

 

[trophywench]

They aren't Hobie, not in a hospital research situation, the method there hasn't changed basically - except the insulin clamp itself isn't as cumbersome a collection of kit as it was years ago.

 

[robert@fm]

Surely this is another report from the Department of the Flippin' Obvious (which is associated with the Department of Redundancy Department)? 🙄 We all know that exercise decreases insulin resistance -- well, it does in me anyway...