FIASP in Pump

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Mafu123

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Type 1
Hi, I have posted before about the fact that I have recently started pumping on Medtronic 780g. I am using FIASP insulin in the pump. For the first 8 days everything was going fantastic. Was in range over 70% of the time and was really pleased. Yesterday was a strange day. I ate all the food I have been eating, and giving the same amount of insulin. Thing is my sugars have went high. No matter how much I try to correct, the sugar levels won't come down. I am wondering is it the FIASP? My vile of insulin had been out of the fridge for about 7 days and I used the last of it in latest set change. Checked my infusion sight and set. Can't get to the bottom of it? I am beginning to wonder is it the FIASP? the only new thing I notices was that I started to feel a stinging sensation when I delivered a bolus. I am wondering should I go of FIASP and back on NV. Any help would be appreciated.
 
Hi @Mafue
I have not used FIASP in my 780 but in my previous pump I tried it and got some very skanky sites and so insulin just did not work so well and levels remained high in those circumstances.

Another thought for the 780. What have you got your max basal per hour set at? I was finding the pump was not bringing down highs and also I was getting woken by alarms saying it had been at max delivery for 7 hours so do a BG. I increased my max basal and the highs now come down more quickly. The pump suggests that you check this out with your HCP.

I hope that helps.
 
I do find that Fiasp appears to turn to water when levels are high.
Actually, it seems it is just really slow to respond at high levels and can plummet after an hour or 90 minutes.
I don't know what this means for closed looping.
 
I tried Fiasp for a while, but seemed to become slightly resistant to it after a couple of weeks. Which was the start of it going downhill and misbehaving. I switched back to NR after 3 vials.

Modern insulins would fine out of the fridge for 28 days at normal ambient temps, so it shouldn’t have been that?

It works brilliantly for some though. I think @Pumper_Sue found it helped to change infusion sites every 2 days rather than every 3 days?
 
Mafue123 said:
Hi, I have posted before about the fact that I have recently started pumping on Medtronic 780g. I am using FIASP insulin in the pump. For the first 8 days everything was going fantastic. Was in range over 70% of the time and was really pleased. Yesterday was a strange day. I ate all the food I have been eating, and giving the same amount of insulin. Thing is my sugars have went high. No matter how much I try to correct, the sugar levels won't come down. I am wondering is it the FIASP? My vile of insulin had been out of the fridge for about 7 days and I used the last of it in latest set change. Checked my infusion sight and set. Can't get to the bottom of it? I am beginning to wonder is it the FIASP? the only new thing I notices was that I started to feel a stinging sensation when I delivered a bolus. I am wondering should I go of FIASP and back on NV. Any help would be appreciated.
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Fiasp is best kept in the fridge until 20 mins before use.
The weather has been very hot for the last few days so more than likely you have cooked it anyway.
If the Fiasp is stinging then make sure you have delivery speed set to the slowest, that cured the problem for me 🙂
Make sure you do a basal test as things do change.
 
Using fiasp in pump for last 3 years, not any any issues with it & much prefer it over novorapid.

Stick with it, if it's stinging then something isn't right so change sites
 
Thanks for the replies everyone. I changed to a new vial of insulin last night and sugars came right back down immediately. So far today they have been back in range, so I assume this was the problem. I also changed the delivery on my pump from fast to slow which has helped to. Thanks for the tip about leaving it in fridge until 20 minutes before a change.

Has anyone got any advice what to do after I bring FIASP out of the fridge? I mean in regard to storage to stop the hot weather cooking it? I have found FIASP has worked really well for me. I bolus right before a meal and it works great, so I'd be very reluctant to go back to NR. I will see how this new vial goes and work from there.

Again, love being no the new pump. It has made such a big difference for me. I have particularly enjoyed the temp Basel feature. Still waiting for my sensors to arrive from Medtronic, so I'm excited to loop.
 
Why not just put the vial back in the fridge after you have done the set change?
 
Mafue123 said:
Has anyone got any advice what to do after I bring FIASP out of the fridge? I mean in regard to storage to stop the hot weather cooking it?
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Put it back in the fridge after use?
 
I have looked this up and it says you can put it back in fridge? Sounds like a good option to me! Do we reckon that this would preserve it better?
 
Why would it be any different to taking it out with you on a cold day. Insulin is probably most stable at fridge temperature, so I wonder where you got the idea from that you can't put it back in the fridge.
 
Mafue123 said:
Has anyone got any advice what to do after I bring FIASP out of the fridge? I mean in regard to storage to stop the hot weather cooking it? I have found FIASP has worked really well for me. I bolus right before a meal and it works great, so I'd be very reluctant to go back to NR. I will see how this new vial goes and work from there.
Click to expand...
Just fill your cartridge and put the vial back in the fridge until next needed.
 
rebrascora said:
Why would it be any different to taking it out with you on a cold day. Insulin is probably most stable at fridge temperature, so I wonder where you got the idea from that you can't put it back in the fridge.
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I obviously had the wrong idea. I think you made your point.
 
I find my insulin is full of bubbles if I try to fill my pump with a vial straight from the fridge which is why it is a no no.
You could keep it in the fridge and take it out the night before a pump change but I found that too much of a faff.
You could keep it in a Frio bag.
Or just keep it out if direct sunlight and away from radiators.
 
helli said:
I find my insulin is full of bubbles if I try to fill my pump with a vial straight from the fridge which is why it is a no no.
Click to expand...
Is that particular to vials of Fiasp because I have never noticed it with pen cartridges and I usually use those straight from the fridge. I appreciate that ensuring there are no bubbles in your pump reservoir may be more important than with MDI although I am not sure why.
 
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