Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
One of the necessary ingredients of an artificial pancreas is faster absorption of rapid-onset bolus insulin. Today?s ?fast? insulins reach their peak blood levels in 60 minutes after injection or infusion bolus, and it takes another 20 to 30 minutes to achieve their maximum glucose-lowering effect. That?s quite a contrast to insulin secreted by a normally functioning human pancreas, which deploys the hormone into the bloodstream within five to 10 minutes of your first bite.
The search for faster insulin absorption centers on two broad areas of research. One focuses on figuring out how to produce a stable supply of insulin monomers, the ?active ingredient? in insulin that allows it to control and direct glucose. The other seeks to speed up absorption by changing the injection device and technique so that insulin is delivered in a way that will disperse it faster. Intradermal injection or infusion ? which dispenses insulin into the first layers of the skin ? is one of the methods that is being explored as a means of delivering the insulin more quickly.
http://insulinnation.com/faster-insulin-short-and-sweet/#.UVH4IBzASSo
The search for faster insulin absorption centers on two broad areas of research. One focuses on figuring out how to produce a stable supply of insulin monomers, the ?active ingredient? in insulin that allows it to control and direct glucose. The other seeks to speed up absorption by changing the injection device and technique so that insulin is delivered in a way that will disperse it faster. Intradermal injection or infusion ? which dispenses insulin into the first layers of the skin ? is one of the methods that is being explored as a means of delivering the insulin more quickly.
http://insulinnation.com/faster-insulin-short-and-sweet/#.UVH4IBzASSo
