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Dagafloxin

jtg1964

jtg1964

Well-Known Member
Relationship to Diabetes
Type 1
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She/Her
Hi has anyone had any success with this drug? Metformin doesn't agree with me and hasn't lowered my sugar levels. Type 2 ...size 8...struggling tbh.
 
jtg1964 said:
Hi has anyone had any success with this drug? Metformin doesn't agree with me and hasn't lowered my sugar levels. Type 2 ...size 8...struggling tbh.
Click to expand...
Do you mean dapagliflozin?
It works in a different way to metformin as it encourages to kidneys to remove excess glucose via urine, people need to make sure they drink plenty otherwise they may become dehydrated and it is not recommended people go too low carb but the around 130g per day as suggested low carb is would normally be OK. There is a risk of UTI as urine is more 'sugary from excreted excess glucose' and bacteria and yeasts just love that environment.
I think many find it help reduce blood glucose along with dietary changes.
What is your HbA1C? Have you actually started on the medication?
 
@jtg1964 welcome to the forum. I was put on dapagliflozin in September in my case it was in addition to metformin. I had only been on metformin for 3 weeks when it was added. I was told it was partly because it improved cardiovascular health. I find i do pee more. My second reading at end of July was 64 and the reading when I was put on dapagliflozin was 58. I am on 2 x metformin. The dose of 4 upset my stomach. My reading now is 44. I don't like the fact I pee more as when first put on metformin I did not pee at night I am also unsettled as to how many carbs to eat. I had previously lost weight by eating 80 to 120. Unlike you I could do with losing more. I was told it was a new drug that had a lot of benefits. I'm due to discuss what happens next, next month.
What is your hba1c ?
 
HBA1C is my blood test results today...61. Thanks for that. I will probably try it. I feel like coming off the meds for 3 months to see if I can put weight on.
 
Leadinglights said:
Do you mean dapagliflozin?
It works in a different way to metformin as it encourages to kidneys to remove excess glucose via urine, people need to make sure they drink plenty otherwise they may become dehydrated and it is not recommended people go too low carb but the around 130g per day as suggested low carb is would normally be OK. There is a risk of UTI as urine is more 'sugary from excreted excess glucose' and bacteria and yeasts just love that environment.
I think many find it help reduce blood glucose along with dietary changes.
What is your HbA1C? Have you actually started on the medication?
Click to expand...
Yes HBA1C is my blood results today 61. Thank you for your reply.
 
yes im on it 10mg a day and it works well but have found i pee a lot has cut my sugar levels a lot
 
I take dapagliflozin alongside metformin and I reported my starting it here.

Docb

Thread 'Annual Review and starting Dapagliflozin'

Annual review this morning and a great chat with a new nurse who has clearly had some training but was quite happy to listen and ask questions of me to find out more. All is well generally, but together we decided that there would be merit in trying to check my HbA1c. My current level (55 mmol/mol) is perfectly acceptable for somebody of my age but the upward trend of my blood glucose levels generally together with the possibility that worsening neurological symptoms may be blood glucose related, indicated adding some medication to try and halt the progression. An SGL-2 is suggested and...
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still the same, so I would say it works for me!
 
jtg1964 said:
Thank you all. Positive feedback.
Click to expand...
Even though you still need to keep a watchful eye on carbs if you need to put weight on then making sure you have plenty protein and healthy fats, avocado, eggs, nuts, full fat dairy, cheese.
 
@jtg1964 until a few weeks ago I was still having mild diarrhea although it has stopped. I've assumed it was the metformin I was still taking. I'm on 10mg. Some people reduce their BG without medication. I have also now been put on a statin.
Good luck
 
Hi @jtg1964
Ok so the medication your asking about wasn’t the same SGLT2 inhibitor that I was taking earlier on this year
we are all different, but for me it wasn’t so good TBH, however we are all different and I recently I was chatting to an old friend (not on here)
he is taking it and has had very positive results using SGLT2 inhibitor
 
I'm about to start on Dapagliflozin today - 10mg od. I was started on Metformin about a year or more ago, but could not deal with the side effects. I had diarrhoea for months rather than weeks so I stopped it completely and never went back so to speak. However after a minor operation in November last year and my blood was tested then and the surgeon was not happy ! I was summoned back to the GP for another issue in my blood (polycythemia - too many red blood cells) and they sent me for a fresh blood test for Diabetes. My sugars were at 115 ! so I am to start this drug. I am pretty scared of it to be honest especially as a side effect is an increase in red blood cells - but the GP has said my risk of this is low compared to issues with Diabetes. I am going to take it at night so I can remember to take it every day, and am tightening up my diet more - less (or no) bread, less pasta, less carbs in general - going to eat a lot more vegetables, increase my protein and increase my exercise. I already drink up to 4 litres of water a day - a left over from doing a VLCD in the past. My biggest fear is the actual eating - I want to lose weight too so am adapting another VLCD - I am not going to be so strict with it so am adding in extra food like the vegetables and protein etc and whilst having the meal replacements for breakfast and lunch will have a meal in the evening. Fingers crossed it all works.
 
Briarrose said:
I'm about to start on Dapagliflozin today - 10mg od. I was started on Metformin about a year or more ago, but could not deal with the side effects. I had diarrhoea for months rather than weeks so I stopped it completely and never went back so to speak. However after a minor operation in November last year and my blood was tested then and the surgeon was not happy ! I was summoned back to the GP for another issue in my blood (polycythemia - too many red blood cells) and they sent me for a fresh blood test for Diabetes. My sugars were at 115 ! so I am to start this drug. I am pretty scared of it to be honest especially as a side effect is an increase in red blood cells - but the GP has said my risk of this is low compared to issues with Diabetes. I am going to take it at night so I can remember to take it every day, and am tightening up my diet more - less (or no) bread, less pasta, less carbs in general - going to eat a lot more vegetables, increase my protein and increase my exercise. I already drink up to 4 litres of water a day - a left over from doing a VLCD in the past. My biggest fear is the actual eating - I want to lose weight too so am adapting another VLCD - I am not going to be so strict with it so am adding in extra food like the vegetables and protein etc and whilst having the meal replacements for breakfast and lunch will have a meal in the evening. Fingers crossed it all works.
Click to expand...
You could have a look at this link which will give you some ideas of what you can eat and still be within the suggested no more than 130g carbs per day, with the medication you have been prescribed then very low carb is not recommended. https://lowcarbfreshwell.com/ so be careful if you are thinking of meal replacement. @Drummer did not find them particularly successful but others have.
Did you have a HbA1C as that is not very accurate if you have too many red blood cells as it is a measure of the glucose attached to the red blood cells so the result may be an over estimate. There is another test which is sometimes done instead, the fructoseamine test.
 
Leadinglights said:
You could have a look at this link which will give you some ideas of what you can eat and still be within the suggested no more than 130g carbs per day, with the medication you have been prescribed then very low carb is not recommended. https://lowcarbfreshwell.com/ so be careful if you are thinking of meal replacement. @Drummer did not find them particularly successful but others have.
Did you have a HbA1C as that is not very accurate if you have too many red blood cells as it is a measure of the glucose attached to the red blood cells so the result may be an over estimate. There is another test which is sometimes done instead, the fructoseamine test.
Click to expand...
Thank you. No just had simple blood tests and the first marker the GP picked up on was the red blood cells excess.... but apparently it is quite normal for me to be just over the parameters, but this one time it was extremely high. At the last blood test done last week, before they chose my medication it must have been back down to my "normal". The HbA1C was done at the same time with the result of 115 - hence this new medication. I am to be on it for a few weeks and due another blood test just before I see the diabetic nurse in March. I will check out that website - sounds interesting. I did think that the VLCD would be low carb too - hence adding in some extra food, but of course its getting the right kind of food - s so this will be very helpful. I have just got to take things more seriously this time.
 
@Briarrose Just to be clear, I did lose weight doing the shake and low calorie diet, but my HbA1c was a little higher than expected. I did the diet for about 2 months, it was not difficult, but by the time of the bloodtest I was eating a tiny meal and having one shake a day, fasting for 22 hours a day, so it was quite severe and I did feel better once I got my test results and decided to stop.
I think it was because my carbs usually come from salad, veges, stirfry, and the milk and whatever is the carbs in the shakes was too easy to absorb, so my blood glucose levels were spiking.
That was all on diet only, no drugs, so it might be different for those who are taking tablets.
 
jtg1964 said:
Hi has anyone had any success with this drug? Metformin doesn't agree with me and hasn't lowered my sugar levels. Type 2 ...size 8...struggling tbh.
Click to expand...

Have you been losing weight without meaning to @jtg1964 ?

Were you always slim? And did they investigate the possibility that you may have another form of diabetes other than T2?

Hope you can find a mix of meds and menu that suits you and meets the needs of all your health conditions 🙂
 
Drummer said:
@Briarrose Just to be clear, I did lose weight doing the shake and low calorie diet, but my HbA1c was a little higher than expected. I did the diet for about 2 months, it was not difficult, but by the time of the bloodtest I was eating a tiny meal and having one shake a day, fasting for 22 hours a day, so it was quite severe and I did feel better once I got my test results and decided to stop.
I think it was because my carbs usually come from salad, veges, stirfry, and the milk and whatever is the carbs in the shakes was too easy to absorb, so my blood glucose levels were spiking.
That was all on diet only, no drugs, so it might be different for those who are taking tablets.
Click to expand...
Thank you Drummer. I am just trying to find a way to avoid bread, crisps etc and thought that using up some of the VLCD products I have would be a good way. I don't intend to be on them for long and am not as strict with it ie only using shakes and bars. I am adding in a small meal with the family in the evening and raw veg as snacks in the day. I am due a blood test in early March so am hoping that there will be a change on this medication and changing the diet. The only real bugbear I have whilst taking the medication is the best time to take the Dapagliflozin - am taking it at night but of course urine production is increased at night without medication, but not sure if it will be much different during the day. Its a bit of trial and error with both for me right now but hopefully I will get it clearer/better in the next couple of weeks.
 
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