Basal-Bolus Versus Once, Twice, and Even Three Times A Day of Long-Acting Insulin (Type 2)

[Northerner]

Satoru Tsujii, MD, PhD, of the department of endocrinology at Tenri Hospital in Japan, and colleagues evaluated data from the Diabetes Distress and Care Registry on 757 adults (mean age, 65.7 years) with type 2 diabetes (mean HbA1c level, 7.8%; mean duration of insulin therapy, 11.3 years) who presented to Tenri Hospital to determine the association between four insulin regimens and increases in HbA1c and insulin dose.

They investigated the association between four insulin regimens and increase in HbA1c and insulin dose in a real-life clinical setting because there is no data about them among insulin regimens.

http://www.diabetesincontrol.com/ba...ven-three-times-a-day-of-long-acting-insulin/

 

[mikeyB]

Sounds a bit counter-intuitive, every insulin regime causing an increase in A1c. Bad dietary advice?

What were the confounders that they adjusted for? Who knows? Or was this simply a poor abstract of the actual study?