• Please Remember: Members are only permitted to share their own experiences. Members are not qualified to give medical advice. Additionally, everyone manages their health differently. Please be respectful of other people's opinions about their own diabetes management.
  • We seem to be having technical difficulties with new user accounts. If you are trying to register please check your Spam or Junk folder for your confirmation email. If you still haven't received a confirmation email, please reach out to our support inbox: support.forum@diabetes.org.uk

Anything to know about Tresiba?

Status
This thread is now closed. Please contact Anna DUK, Ieva DUK or everydayupsanddowns if you would like it re-opened.

MarkGeordie

Well-Known Member
Relationship to Diabetes
Type 1
After discussion with my DSN regarding a lot of during the night hypos, even though nothing has changed in terms of usual diet, exercise, etc, it’s been recommended I change from levemier to tresiba.

Is there anything I should know?

DSN give minimum information.
 
Is there anything I should know?

It's a once daily injection rather than Levemir's twice a day. So I think Levemir gives you more flexibility (you can reduce the night time dose while keeping the daytime one the same, for example). However, if Levemir's not working well for you then I guess it's worth a try. (The wikipedia article suggests that in a trial comparing it with Lantus, people using Tresiba had fewer night time hypos.)
 
What would you like to know?

Its an extra long acting insulin and therefore any dose adjustments take 3 days to take effect, due to this it isn't adjustable to take into account any extra exercise so you may find you need to adjust your bolus insulin for a minimum of 24 hours after should instances like that occur

I like it though and it's the only basal I've ever used
xx
 
I used Lantus before changing to Tresiba. I do prefer it, though as @Kaylz has said, any adjustments take a few days to take effect before you can see any change in level. I take mine before i go to bed.
 
I was only on 1 injection in the evening of levemier anyway.

First injection of tresiba tonight.
 
I was only on 1 injection in the evening of levemier anyway.

First injection of tresiba tonight.
Hi Mark,

Would you be able to give us an update on dosage? My swap turned out to be like for like, 20u lantus to 20 units tresiba. I really like tresiba, no need to to worry about taking it at the same time every day, if I fancy a lie in, I just take it when I get around to waking up. It's got a huge overlap. However, it was problematic at the time I swapped because the nurse believed the dose needed to be a lot less than what I was taking before on lantus. It takes 3 days for any changes to come through.
 
Yes my DSN has asked me to go down by 20% and then she’s calling me half 9 Tues morning to review.
 
Yes my DSN has asked me to go down by 20% and then she’s calling me half 9 Tues morning to review.
OK I hope it goes well for you.

Just to explain what I mean about a 3 days lag on changing doses. If you do need to change the dose, say it was taken at 9am monday, this won't show up until 9 am wednesday or perhaps a little bit before. They don't usually recommend changing doses in tresiba any sooner than I think 4-5 days, cos you need to give it time to see if it's the righ amount. In the meantime if it's too little, I used to rely in increasing boluses, if it's too much then it would be a matter of eating more or taking less bolus.
 
Thanks for that. It makes sense. I will monitor the situation and hopefully won’t be too long before I find the right dose.
 
How has it been going over the weekend @MarkGeordie?

Deffo believe that the 20% reduction was not the best advice from the DSN but I can understand her hesitation to do like for like.

Thursday night was the first night of Tresiba so last night (Saturday) was the third. I’m running higher than usual with having to add in correction dosages, so is it safe to make the first adjustment and increase the night time injection? How much by?

I hate change.
 
Deffo believe that the 20% reduction was not the best advice from the DSN but I can understand her hesitation to do like for like.

Thursday night was the first night of Tresiba so last night (Saturday) was the third. I’m running higher than usual with having to add in correction dosages, so is it safe to make the first adjustment and increase the night time injection? How much by?

I hate change.

Unfortunately I don’t think anyone here can advise. Perhaps try to speak to your nurse tomorrow? Must be frustrating knowing there is such a lag in any changes taking effect. :(
 
Deffo believe that the 20% reduction was not the best advice from the DSN but I can understand her hesitation to do like for like.

Thursday night was the first night of Tresiba so last night (Saturday) was the third. I’m running higher than usual with having to add in correction dosages, so is it safe to make the first adjustment and increase the night time injection? How much by?

I hate change.
When I went onto tresiba, the consultant was adamant that it should be like for like, but the nurse said 20 % less than lantus I was on. Nurse was the one seeing me after consultant appointment so I went with the 20% reduction. I don't think tresiba works fully anyway the first time you take it so that will have to be factored in too. It takes 2 days for it to achieve full potential. I ended up taking extra bolus (humalog) with each meal to pre-empt the rise between meals, rather than correcting the high each time, because I had to correct the high, PLUS add in extra for the shortfall just to get back in range at next meal. Night-time was a problem, cos blood sugar would be rising during sleeping.

For me and I think many other people on insulin will probably confirm this, that just 1 unit change on basal can make a massive difference to results. It literally wasn't until I got back to exactly the same does as before that everything settled back to normal levels. I do understand the caution with the 20%, but at 20 units, that would be 4 units short and if one can only adjust every 4 days it could take at least 12 days to sort.

Best talk with your nurse and see what she says, at least you know that your current tresbia dose is too little.
 
Thanks to you both.

She’s ringing me Tuesday morning anyway so I’ll talk to her then.

I’ll have to ask her how much I should increase for over the coming weeks just so I can do it myself without having to schedule a call each time.
 
I'm a 1 unit at a time increaser too as it really can make that big difference, if you were comfortable adjust your previous then you should feel no differently about adjusting Tresiba, running higher for a few days with increasing by only 1 unit at a time is better than whacking in 2 extra units and ending up hypoing a lot a few days later, I do talk from experience too as I'll have been using it 4 years in little over a week xx
 
think tresiba has a slightly longer half life than Lantus, so you can take it at any time of the day and is said to be superior, less prone to give hypos, but because of the slow half life have to be cautious in increasing your dosages, as others have commented above.
 
think tresiba has a slightly longer half life than Lantus, so you can take it at any time of the day and is said to be superior, less prone to give hypos, but because of the slow half life have to be cautious in increasing your dosages, as others have commented above.

It was initially marketed as a 48hr super-long-acting analogue, but the recommendations were to take it every 24 hours.

It has some data for reduced incidence of hypos, and it seems to suit people with a fairly ‘flat’ basal requirement. We have a few forum members who like it and do well on it 🙂
 
Status
This thread is now closed. Please contact Anna DUK, Ieva DUK or everydayupsanddowns if you would like it re-opened.
Back
Top