Gone from diagnosed type 2 to now being type 1

[Andy HB]

They don't even share the same symptoms - T1 causes weight loss and DKA, T2 causes weigh gain.

I'm sorry but I think you're in error on that. I'm a Type 2 and had severe insulin resistance. I'd lost a stone in weight prior to diagnosis and I'd also been experiencing the classic ketone smell on the breath. It wasn't the full blown DKA as you'd get when there is no insulin present, but I was 'getting there' (I'd also had a couple of times when I was vomiting for no apparent reason).

Once I'd sorted my weight out, it became apparent that my insulin production was actually not that bad and I could get away with not being on any medication.

Andy 🙂

 

[trophywench]

Technically, sorry Deus, they are not a T1 if they stop producing insulin because THAT depends on what kills the Beta cells.

If it's auto-immune antibodies (ie GAD65 antibodies) then they are T1.

If they haven't got em or had em, (or enough of em, not sure if they are intrisically bad or whether they just gang up and riot, or what) then that means it ain't T1.

It's my understanding that T1s have sheadloads of the ruddy things on diagnosis but once they have done their dirty work, they disappear either entirely or almost entirely, not sure which - but anyhow it has been said you have to do that test within the first 6 months of diagnosis to get a meaninful result. I mean I fully expect that I haven't got any by now, but that doesn't mean I've Shape Changed into T2 or anything else other than T1, does it?

And talking of shape, how do you therefore explain my friend Lanky L(surname) - as she was known at school, she always has been thin and still is now she's 50-odd. She's been T2 for about 10 years now! Tall and slender. We have had quite a succession of thin T2s on the other DSF plus more than several Mature T1s.

Plus I've been similar to a barrel on legs at one time in my life, whilst I've had T1. Certainly not before I was diagnosed though. And it was caused by totally normal classical means - ie eating far too much too fattening food. So I stopped doing it and got rid of the barrel.

And not every T2 has missing Phase 1 insulin, and not every T2 has insulin resistance, and not every T2 will ever kill all their Beta cells, or need insulin, not every one will have hyperinsulinema to cause weight gain - the list goes on ad nauseam.

In comparison to T2, the mechanism (? is that the word) of T1 is pretty straightforward to understand, notionally that is*. T2 ain't ..... I think it's a list of differing symptoms and causes that are all lumped together for convenience and it'sa wonder anyone gets treated correctly for it since the tests aren't done to establish which bit's gone wrong in the first place.

* and as every T1 will agree it isn't straightforward at all .....

 

[trophywench]

Dizzy Di - so what DID the GAD65 test reveal?

 

[Andy HB]

Technically, sorry Deus, they are not a T1 if they stop producing insulin because THAT depends on what kills the Beta cells.

I've made THAT mistake in the past! (calling a Type 2 who doesn't produce any insulin a Type 1).

 

[mcdonagh47]

I'm sorry but I think you're in error on that. I'm a Type 2 and had severe insulin resistance. I'd lost a stone in weight prior to diagnosis and I'd also been experiencing the classic ketone smell on the breath. It wasn't the full blown DKA
Andy 🙂

Its exceptionally rare for T2s to get DKA ... we get a more deadly version of dehydration and raised glucose called HONK or HHNS

 

[Dizzydi]

Dizzy Di - so what DID the GAD65 test reveal?

I don't know trophywench was not mentioned in letter back to gp. I presume the full blood count is nothing to do with the GAD 65 lol I'm a bit dum at times.

But I will ask consultant when I next see him what it revealed, if anything (same consultant who did initial diagnosis)

 

[cherrypie]

They don't come much thinner than me and I am a Type2.

20% of Type2's do not have a weight problem.

 

[Northerner]

Its exceptionally rare for T2s to get DKA ... we get a more deadly version of dehydration and raised glucose called HONK or HHNS

Why is it 'deadlier' than DKA?

 

[Mark T]

I don't know trophywench was not mentioned in letter back to gp. I presume the full blood count is nothing to do with the GAD 65 lol I'm a bit dum at times.

But I will ask consultant when I next see him what it revealed, if anything (same consultant who did initial diagnosis)

I think full blood count was something to do with anemia/iron levels - this seems to agree: http://www.labtestsonline.org.uk/understanding/analytes/fbc/

 

[Mark T]

...If they haven't got em or had em, (or enough of em, not sure if they are intrisically bad or whether they just gang up and riot, or what) then that means it ain't T1...

Although I did read an article that indicated that Type 2's shouldn't have any GAD antibodies at all. So if you have even a small smidgen of them you do have some element of Type 1, just if it's really small it's going to take lots of time before you end up on insulin, whereas if you have bucket loads you are likely to be on insulin pretty soonish.

 

[mcdonagh47]

Why is it 'deadlier' than DKA?

because a greater proportion of T2s who suffer from HONK die from it as a result, as opposed to the proportion of T1s with DKA who die from that. HONK has a staggering death rate of 58% according to one study.
HONK/HHNS carries off a significant number of elderly T2s,especially in Nursing Homes, they forget/get confused about insulin injections and get dehydrated as well.

 

[Northerner]

because a greater proportion of T2s who suffer from HONK die from it as a result, as opposed to the proportion of T1s with DKA who die from that. HONK has a staggering death rate of 58% according to one study.
HONK/HHNS carries off a significant number of elderly T2s,especially in Nursing Homes, they forget/get confused about insulin injections and get dehydrated as well.

Thanks for clarifying, I'd heard of it but hadn't realised how dangerous it was.