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- Relationship to Diabetes
- Type 1
"Looking at participants in the Framingham Heart Study, we identified that the correlation between the ideal identified obesity-related gene variant and body mass index elevated significantly as the year of birth of participants increased," says James Niels Rosenquist, MD, PhD, of the Massachusetts Common Hospital (MGH) Division of Psychiatry, lead author of the report. "These results -- to our understanding the 1st of their type -- suggest that this and maybe other correlations amongst gene variants and physical traits might very substantially based on when people were born, even for those born into the exact same families."
The authors note that most studies of interactions amongst genes and the environment have looked at variations inside certain birth cohorts -- groups born through a unique span of years -- which would not account for changes in the bigger atmosphere that take place over time. To investigate regardless of whether diverse conditions experienced by unique age groups could alter the influence of a gene variant, they analyzed data from participants in the Framingham Offspring Study -- which follows the children of participants in the original study -- gathered among 1971, when participants ranged in age from 27 to 63, and 2008.
http://www.macroinsider.com/science...f-obesity-associated-gene-variant-h19791.html
The authors note that most studies of interactions amongst genes and the environment have looked at variations inside certain birth cohorts -- groups born through a unique span of years -- which would not account for changes in the bigger atmosphere that take place over time. To investigate regardless of whether diverse conditions experienced by unique age groups could alter the influence of a gene variant, they analyzed data from participants in the Framingham Offspring Study -- which follows the children of participants in the original study -- gathered among 1971, when participants ranged in age from 27 to 63, and 2008.
http://www.macroinsider.com/science...f-obesity-associated-gene-variant-h19791.html