I think the different cgm systems have diffferent startup schemes. Which are you using?
FWIW, this applies to Medtronic Guardian:
Ideally you would fit a new sensor, such that BG levels are stable during first calibration. For the one I use, Medtronic Guardian cgm, it wants first calibration about 1.5 hrs after start of new sensor (when interstitial fluid has properly presented itself around the sensor lead), then a second calibration 6 hours after first. For me, this is means I set new sensors a few hours after a meal or a couple hours before the next.
I would say, don't stress while you're learning timing. During first few hours (0-12 hrs) it's not uncommon for me to restart sensor (turn off exisitng sensor and tell pump I have new sensor) when SG (sensor glucose) readings are flat and there is large difference between BG (meter) and SG.......this takes place w/one finger prick and of course, the "clock" resets on sensor age. Hope this helps.