What should be the antihypertensive drug of choice in diabetic patients?

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Northerner

Admin (Retired)
Relationship to Diabetes
Type 1
Summary
It has long been known that antihypertensive drugs may affect blood glucose in a differential manner. In particular new onset diabetes is significantly increased in association with the use of thiazides or beta-blockers, respectively, compared to placebo, whereas treatment with angiotensin-conversion-enzyme-inhibitors or angiotensin-receptor-blockers is associated with a lower than expected frequency, as also assessed in several meta-analyses. In line with these notions, the NAVIGATOR Trial was the first to report a significant preventive effect of an angiotensin-receptor-blocker on new onset diabetes evaluated as a primary outcome in a prospective randomized study.

http://onlinelibrary.wiley.com/doi/10.1002/dmrr.2355/abstract
 
Oh good, that's what you and I take for it Alan ! LOL

Our Guidelines say ACE/ARB as first line defence anyway for any type of higher than wanted BP, or to ward high BP off anyway once you are diabetic, hence I went on it as soon as I had a decent consultant.
 
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