What Do Marine Snails and Insulin Have in Common? New Approach to Treat Diabetes?

Status
Not open for further replies.

Northerner

Admin (Retired)
Relationship to Diabetes
Type 1
The cone snails are predators of the sea. They capture fish by injecting a venom into the prey that consists of a cocktail of different substances. The single components of the snails' venom, so-called conopeptides, are known for their extraordinary pharmacological properties and potential.

One example is Ziconotid (Prialt), a conopeptide that is prescribed as a pain medicine. That makes it one of the first medicines to contain substances from marine organisms. In collaboration with scientists from Canada and the USA, research teams at the Universities of Kiel, L?beck, and G?ttingen have examined the venom of the cone snail Conus striatus. They were able to demonstrate that a certain peptide (Conkunitzin-S1) alters the release of insulin in the pancreas cells. Their findings were recently published in the scientific magazine EMBO Molecular Medicine.

http://www.sciencedaily.com/releases/2012/05/120510100228.htm
 
Status
Not open for further replies.
Back
Top