What causes type 1 diabetes?

[Amity Island]

Notably, comparing their findings to a clearinghouse of sequencing data for the type 1 diabetes microbiome indicates that exposure to this bacterium at an early age increases the risk to develop type 1diabetes in children at genetic risk of the disease.

What causes type 1 diabetes?

A Boston College researcher has identified a gut microbe that could accelerate the autoimmune disease, which affects 1.6 million Americans.

www.bc.edu

 

[Inka]

Interesting @Amity Island My consultant thinks Type 1 starts in the gut (as do I). There was a project a few years ago about the microbiome and Type 1. I can’t remember the name of it, but the guy involved went to Africa, I think, to study the microbiomes of particular groups of people.

 

[Amity Island]

Interesting @Amity Island My consultant thinks Type 1 starts in the gut (as do I). There was a project a few years ago about the microbiome and Type 1. I can’t remember the name of it, but the guy involved went to Africa, I think, to study the microbiomes of particular groups of people.

@rebrascora has mentioned this and the vagus nerve a few times on the forum.

It's looking like what you eat really does effect your health in all sorts of ways. Those health "freaks" have been proven right. Look in any supermarket and almost everything on the shelves is junk.

 

[Inka]

I’m googling trying to find the guy I’m thinking of @Amity Island but failing so far. I think he lived with the Hadza for a time and was trying to replicate their microbiome by eating their diet. I’ve got a feeling he also had a faecal transplant but I might be muddling it with another person.

It makes sense to me that the microbiome is involved. That would fit with formula fed babies being at higher risk and babies born by C section.

 

[Amity Island]

I’m googling trying to find the guy I’m thinking of @Amity Island but failing so far. I think he lived with the Hadza for a time and was trying to replicate their microbiome by eating their diet. I’ve got a feeling he also had a faecal transplant but I might be muddling it with another person.

It makes sense to me that the microbiome is involved. That would fit with formula fed babies being at higher risk and babies born by C section.

The experts have maintained for decades that diabetes isn't caused by eating sugar, but is it?

 

[Inka]

The experts have maintained for decades that diabetes isn't caused by eating sugar, but is it?

No,I don’t think so. The formula fed babies would have a ‘leakier’ gut, allowing the passage of rogue proteins/viruses/whatever, and the C section babies miss out on their mother’s microbiome. Poor diet isn’t good for health, but I don’t think that’s the root issue.

 

[Amity Island]

Diet is a strong modifier of microbiome and mucosal microenvironment in the gut. Recently, components of western-type diets have been associated with metabolic and immune diseases. Here, we studied how high-sugar diet (HSD) consumption influences gut mucosal barrier and immune response under steady state conditions and in a mouse model of acute colitis. We found that HSD significantly increased gut permeability, spleen weight, and neutrophil levels in spleens of healthy mice.

Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling

Diet is a strong modifier of microbiome and mucosal microenvironment in the gut. Recently, components of western-type diets have been associated with metabolic and immune diseases. Here, we studied how high-sugar diet (HSD) consumption influences gut ...

www.ncbi.nlm.nih.gov