Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Nearly half of all diabetics suffer from neuropathic pain, an intractable, agonizing and still mysterious companion of the disease. Now Yale researchers have identified an unexpected source of the pain and a potential target to alleviate it.
A team of researchers from Yale and the West Haven Veterans Affairs Medical Center describes in the May 15 issue of the Journal of Neuroscience how changes in the structure of dendritic spines ? microscopic projections on the receiving branches of nerve cells ? are associated with pain in laboratory rats with diabetes.
"How diabetes leads to neuropathic pain is still a mystery," said Andrew Tan, an associate research scientist in neurology at the Yale School of Medicine and lead author of the study. "An interesting line of study is based on the idea that neuropathic pain is due to faulty 'rewiring' of pain circuitry."
http://www.frca.co.uk/content.aspx?pageid=1&content=1717&bindType=default
A team of researchers from Yale and the West Haven Veterans Affairs Medical Center describes in the May 15 issue of the Journal of Neuroscience how changes in the structure of dendritic spines ? microscopic projections on the receiving branches of nerve cells ? are associated with pain in laboratory rats with diabetes.
"How diabetes leads to neuropathic pain is still a mystery," said Andrew Tan, an associate research scientist in neurology at the Yale School of Medicine and lead author of the study. "An interesting line of study is based on the idea that neuropathic pain is due to faulty 'rewiring' of pain circuitry."
http://www.frca.co.uk/content.aspx?pageid=1&content=1717&bindType=default