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Tumor Necrosis Factors Predict Kidney Disease in Diabetes

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Northerner

Admin (Retired)
Relationship to Diabetes
Type 1
Levels of circulating tumor necrosis factor receptor 1 and 2 (TNFR1 and TNFR2) predict kidney disease in both type 1 and type 2 diabetes, according to the results of two 12-year studies.

The cumulative incidence of end-stage renal disease (ESRD) among those with type 2 diabetes who had the highest quartile of TNFR1 at baseline was 54% at 12 years, compared with only 3% for the other quartiles (P< 0.001), reported Andrzej S. Krolewski, MD, PhD, from the Joslin Diabetes Center in Boston, and colleagues.

http://www.medpagetoday.com/Endocrinology/Diabetes/30814
 
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