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Researchers have hailed a breakthrough in the treatment of a common, incurable disease that causes hand deformities by bending the fingers firmly into the palm.
A clinical trial at Oxford and Edinburgh Universities found that a drug used for rheumatoid arthritis appeared to drive Dupuytren’s disease into reverse when used early on, a result described as a potential “gamechanger” for patients.
“We are very keen to pursue this,” said Prof Jagdeep Nanchahal, a surgeon scientist who led the trial at Oxford’s Kennedy Institute of Rheumatology. “This is a very safe drug and it’s important patients can access a treatment if it’s likely to be effective.”
The disease is named after the French surgeon Baron Dupuytren, who besides claiming the honour of treating Napoleon’s haemorrhoids, acquired the arm of a dead man he had “kept an eye on”, not wishing to lose the opportunity to investigate his permanently retracted fingers. Dupuytren’s affects about 5 million people in the UK, half of whom have early stage progressive disease.
A clinical trial at Oxford and Edinburgh Universities found that a drug used for rheumatoid arthritis appeared to drive Dupuytren’s disease into reverse when used early on, a result described as a potential “gamechanger” for patients.
“We are very keen to pursue this,” said Prof Jagdeep Nanchahal, a surgeon scientist who led the trial at Oxford’s Kennedy Institute of Rheumatology. “This is a very safe drug and it’s important patients can access a treatment if it’s likely to be effective.”
The disease is named after the French surgeon Baron Dupuytren, who besides claiming the honour of treating Napoleon’s haemorrhoids, acquired the arm of a dead man he had “kept an eye on”, not wishing to lose the opportunity to investigate his permanently retracted fingers. Dupuytren’s affects about 5 million people in the UK, half of whom have early stage progressive disease.
Treatment for finger-bending disease may be ‘gamechanger’
Clinical trial seems to show Dupuytren’s disease reversed by rheumatoid arthritis drug
www.theguardian.com