Toxic Byproduct May Lead To Decreased Diabetes, Body Weight

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Northerner

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Relationship to Diabetes
Type 1
Discovery may inform new strategies for curbing worldwide obesity epidemic

Researchers at Mount Sinai School of Medicine have identified a common compound in the modern diet that could play a major role in the development of abdominal obesity, insulin resistance, and type 2 diabetes. The findings are published in the August 20, 2012 issue of the Proceedings of the National Academy of Sciences.

The research team, led by Helen Vlassara, MD, Professor and Director of the Division of Experimental Diabetes and Aging, found that mice with sustained exposure to the compound, methyl-glyoxal (MG), developed significant abdominal weight gain, early insulin resistance, and type 2 diabetes. MG is a type of advanced glycation endproduct (AGEs), which is produced when food is cooked with dry heat. AGEs have been found to lower the body?s protective mechanisms that control inflammation.

http://www.redorbit.com/news/scienc...t-may-lead-to-decreased-diabetes-body-weight/
 
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