The enzyme that could help curb chronic kidney disease

[Northerner]

University of South Australia researchers have identified an enzyme that may help to curb chronic kidney disease, which affects approximately 700 million people worldwide.

This enzyme, NEDD4-2, is critical for kidney health, says UniSA Centre for Cancer Biology scientist Dr Jantina Manning in a new paper published this month in Cell Death & Disease.

The early career researcher and her colleagues, including 2020 SA Scientist of the Year Professor Sharad Kumar, have shown in an animal study the correlation between a high salt diet, low levels of NEDD4-2 and advanced kidney disease.

While a high salt diet can exacerbate some forms of kidney disease, until now, researchers did not realise that NEDD4-2 plays a role in promoting this salt-induced kidney damage.

The enzyme that could help curb chronic kidney disease

Researchers have identified an enzyme that may help to curb chronic kidney disease, which affects approximately 700 million people worldwide.

www.sciencedaily.com

 

[mikeyB]

There may be a correlation, but that may not be a cause. That’s ever the problem with correlations. And giving animals a high salt diet is cruel. The majority of animals eat a naturally low salt diet, so god knows what all that salt does to rest of the poor animal.