Telmisartan reverses insulin resistance in mice

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Northerner

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Treating mice fed a high-fat diet with telmisartan reverses insulin resistance and glucose intolerance, but only when the peroxisome proliferator-activated receptor-δ (PPAR-δ) gene is present, according to a study published online Dec. 13 in Diabetes.

Li Li, from the Chongqing Institute of Hypertension in China, and colleagues examined the effects of telmisartan, an angiotensin receptor blocker, on insulin signaling and glucose uptake in wild-type mice and mice lacking the PPAR-δ gene in muscle.

http://medicalxpress.com/news/2013-01-telmisartan-reverses-insulin-resistance-mice.html
 
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