Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Australian scientists have identified a gene that regulates muscle size, a finding that could help unlock therapies for Type 2 diabetes and diseases such as muscular dystrophy, where muscles are weakened and damaged.
Type 2 diabetes occurs when the body no longer controls blood sugar levels properly. We need insulin, a hormone released from the pancreas when we eat, to channel sugar from our blood into our cells.
While researching ways to improve the response of muscle to insulin, Dr Lowenna Holt, Associate Professor Greg Cooney and Professor Roger Daly from Sydney's Garvan Institute of Medical Research were surprised to see that a particular strain of genetically modified mice - missing the Grb10 protein - had large muscles. Even newborn mice missing Grb10 had larger muscles, indicating that this protein regulates muscle development before birth. The results are now published online in The FASEB Journal.
http://www.healthcanal.com/disorder...oach-towards-diabetes-and-other-diseases.html
Type 2 diabetes occurs when the body no longer controls blood sugar levels properly. We need insulin, a hormone released from the pancreas when we eat, to channel sugar from our blood into our cells.
While researching ways to improve the response of muscle to insulin, Dr Lowenna Holt, Associate Professor Greg Cooney and Professor Roger Daly from Sydney's Garvan Institute of Medical Research were surprised to see that a particular strain of genetically modified mice - missing the Grb10 protein - had large muscles. Even newborn mice missing Grb10 had larger muscles, indicating that this protein regulates muscle development before birth. The results are now published online in The FASEB Journal.
http://www.healthcanal.com/disorder...oach-towards-diabetes-and-other-diseases.html