T3D Therapeutics’ drug explores the link between diabetes and Alzheimer’s disease

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Northerner

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There’s a growing consensus that two of society’s most rampant public health issues – Type II Diabetes and Alzheimer’s disease – are intertwined. It’s not all about clearing plaques anymore: Insulin modulation is askew in both diseases, which has led researchers to examine sugar metabolism’s link to cognitive decline.

North Carolina startup T3D Therapeutics is actually repurposing a small molecule drug that was initially being developed for diabetes, and aiming it instead toward Alzheimer’s.

“The similarities of insulin resistance between Type 2 diabetes and Alzheimer’s disease are very striking,” CEO John Didsbury said. After all, they’ve both got amyloid aggregation, oxidative stress, inflammation, neural degeneration and cognitive impairment. Didsbury’s got a grand vision for the efficacy of the small molecule drug: He projects T3D’s once-a-day pill could “slow, stop or reverse the course of Alzheimer’s disease.”

http://medcitynews.com/2015/03/t3d-therapeutics-exploring-link-diabetes-alzheimers-disease/

Sounds like much better value than Afrezza's $1bn if they can come up with something 🙂
 
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