Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
As obesity rates rise, so does the incidence of type 2 diabetes (T2D). In obese individuals and those with obesity-induced T2D, there is an accumulation of immune cells within adipose tissue that results in a low level of chronic inflammation. Gut microbial populations are also altered in these individuals. Weight loss, either through diet or gastric bypass, improves TD2-associated symptoms and shifts the gut microbiota.
A new study in the Journal of Clinical Investigation reports that a population of T cells known as mucosal-associated invariant T (MAIT) cells is altered in patients with T2D and/or severe obesity. MAIT cells are an innate-like T cell population that recognizes bacterial ligands and is enriched in mucosal and inflamed tissues.
http://www.sciencedaily.com/releases/2015/03/150309174825.htm
A new study in the Journal of Clinical Investigation reports that a population of T cells known as mucosal-associated invariant T (MAIT) cells is altered in patients with T2D and/or severe obesity. MAIT cells are an innate-like T cell population that recognizes bacterial ligands and is enriched in mucosal and inflamed tissues.
http://www.sciencedaily.com/releases/2015/03/150309174825.htm