Steroids Not Effective for Mild, Low-Eosinophil Asthma

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Northerner

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Patients with mild, persistent asthma and low eosinophil levels fare no better with inhaled corticosteroids than with placebo, results from the Steroids in Eosinophil Negative Asthma (SIENA) study (NCT02066298) show.

"We've been sending the message that something bad is going to happen if you don't give steroids" to all patients with asthma, said researcher Stephen Lazarus, MD, from the University of California, San Francisco. But "this calls all of that into question."

"We're pretty excited about these results," he told Medscape Medical News, but, he warned, clinicians should proceed with caution.

"We don't want people throwing away their medicines; this is not the definitive study," Lazarus explained. However, "it does make an argument for paying closer attention to the way patients respond. Bottom line: we are moving to the realization that asthma is a heterogeneous disease."

https://www.medscape.com/viewarticle/913412

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Tut! One minute they're telling my that mild hypothyroidism might not need pills, now they're saying my asthma might not need steroid inhalers! 🙄
 
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And how exactly is a GP supposed to assess eosinophil levels in sputum? It’s more pragmatic than that. If regular steroid inhalation suppresses symptoms, then carry on. As both you and I know.
 
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