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Scientists have demonstrated a new way to reprogram adult tissue to become cells as versatile as embryonic stem cells ? without the addition of extra genes that could increase the risk of dangerous mutations or cancer.
Researchers have been striving to achieve this since 2006, when the creation of so-called induced pluripotent (iPS) cells was first reported. Previously, they had managed to reduce the number of genes needed using small-molecule chemical compounds, but those attempts always required at least one gene, Oct42, 3.
Now, writing in Science, researchers report success in creating iPS cells using chemical compounds only ? what they call CiPS cells1.
http://www.nature.com/news/stem-cells-reprogrammed-using-chemicals-alone-1.13416
Researchers have been striving to achieve this since 2006, when the creation of so-called induced pluripotent (iPS) cells was first reported. Previously, they had managed to reduce the number of genes needed using small-molecule chemical compounds, but those attempts always required at least one gene, Oct42, 3.
Now, writing in Science, researchers report success in creating iPS cells using chemical compounds only ? what they call CiPS cells1.
http://www.nature.com/news/stem-cells-reprogrammed-using-chemicals-alone-1.13416