Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
The first patient dosed with VX-880—a stem cell-derived potential therapy to treat type 1 diabetes—has achieved groundbreaking insulin independence at day 270 with an HbA1c of 5.2 percent, according to a recent press release.
This means the patient no longer requires exogenous (external) insulin doses and is producing enough endogenous (internal) insulin to maintain normal blood sugar levels at day 270 of the trial.
In 2021, Vertex Pharmaceuticals Inc. made headlines with earlier results of the same trial: the same patient had experienced a 91% reduction in their daily need for exogenous insulin at day 90.
Still currently in Phase 1/2 of its clinical trial, there is still one caveat to its success: the patient requires immunosuppression therapy to sustain their insulin production. Vertex, however, is confident it will find better ways to manage the immune system around its proprietary product.
This means the patient no longer requires exogenous (external) insulin doses and is producing enough endogenous (internal) insulin to maintain normal blood sugar levels at day 270 of the trial.
In 2021, Vertex Pharmaceuticals Inc. made headlines with earlier results of the same trial: the same patient had experienced a 91% reduction in their daily need for exogenous insulin at day 90.
Still currently in Phase 1/2 of its clinical trial, there is still one caveat to its success: the patient requires immunosuppression therapy to sustain their insulin production. Vertex, however, is confident it will find better ways to manage the immune system around its proprietary product.
Stem Cell Therapy for Type 1 Diabetes: Patient Achieved Insulin Independence on Day 270
On day 270, a patient in the Vertex Pharmaceutical’s clinical trial to treat type 1 diabetes achieved insulin independence.
beyondtype1.org