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Does anyone who takes statins take Co-enzyme Q10? i've read several articles which say that if you take statins, then the Q10 will help your cells and give you more energy as the statins can deplete the body of this stuff, how true is this?
Does anyone who takes statins take Co-enzyme Q10? i've read several articles which say that if you take statins, then the Q10 will help your cells and give you more energy as the statins can deplete the body of this stuff, how true is this?
Q10 is made in the same pathway as cholesterol so statins in addition to lowering cholesterol also lower CoQ10 (and a host of other important substances 😱)
Does anyone who takes statins take Co-enzyme Q10? i've read several articles which say that if you take statins, then the Q10 will help your cells and give you more energy as the statins can deplete the body of this stuff, how true is this?
Marcoff et al did a review of the eviudence in 2007 and concluded there is no proof that Statins reduce Co-Enzyme Q10,. Its a theroretical supposition with no evidence of it happenoing in fact.
] MARCOFF, L., & THOMPSON, P. (2007). The Role of Coenzyme Q10 in Statin-Associated MyopathyA Systematic Review Journal of the American College of Cardiology, 49 (23), 2231-2237 DOI: 10.1016/j.jacc.2007.02.049
Q10 is at its most active in your twenties and has declined by 80 % by the time you reach 60.
Does anyone who takes statins take Co-enzyme Q10? i've read several articles which say that if you take statins, then the Q10 will help your cells and give you more energy as the statins can deplete the body of this stuff, how true is this?
Here's some additional info' taken from Marcoff and Thomson's paper
Statin therapy is frequently limited by myopathic symptoms creating a critical need for strategies to prevent statin myopathy. Coenzyme Q10 supplementation is a simple, attractive therapy that requires an appropriately powered and randomized trial to determine whether CoQ10 eliminates or reduces statin myalgia in symptomatic patients. Simultaneous genetic studies should attempt to determine if genetic variants contribute to the variability in the response to CoQ10 therapy. Studies designed to determine if CoQ10 prevents the onset of myalgia in statin-naive patients are not practical because of the number of subjects that would be required in such a trial. In addition, the absence of pharmacologic grade CoQ10 supplement and a study sponsor makes such a trial difficult. Nevertheless, such trials are the only way to demonstrate conclusively whether or not clinicians should prescribe CoQ10 to their patients on statin therapy.
Footnotes
Dr. Thompson has received research support and speaking honoraria from Merck, Pfizer, AstraZeneca, Schering-Plough, and Kos and owns stock in Merck, Pfizer, and Schering-Plough. This guy has a vested interest in selling Statins
Does anyone who takes statins take Co-enzyme Q10? i've read several articles which say that if you take statins, then the Q10 will help your cells and give you more energy as the statins can deplete the body of this stuff, how true is this?
The overall conclusion of Marcoff's research paper, that is being batted about is ..." The routine use of CoQ10 cannot be recommended in statin-treated patients."
Its the Supplements Industry that is pushing this stuff at us along with cinnamon etc etc etc
The overall conclusion of Marcoff's research paper, that is being batted about is ..." The routine use of CoQ10 cannot be recommended in statin-treated patients."
Its the Supplements Industry that is pushing this stuff at us along with cinnamon etc etc etc
The cinnamon claims have been around for decades. i religiously scattered it on my porridge in the 1900s - I can't say I was aware of it doing any good.
The claims on Supplements and diabetes were investigated by Harvard University about ten years ago and they came back with the conclusion that there wasn't anything in the claims but a couple of things might be worth investigating further ; chromium was one I seem to think.
You have also to be aware of the quantities that have been tested - you might need a sackful of cinnamon a day to get the same effect that the rats, or whatever, got in the tests. Five or so years ago diabetics, and others at risk of heart disease, were being urged to drink two glasses of RED wine a day for the resveraterol content. Turns out in the research it was based on, rats had resveraterol in concentrated powder form. For humans to get the same effect as the rats they would need to drink 12 bottles a night for all the resveraterol there is in red wine.
Also about eight years ago there were warnings about buying food supplements like this from Far Eastern sources - some things, powdered Unicorn Horn or whatever, were lowering bgs but only because they had been laced with crushed up sulfonylureas ( e.g. gliclazide) so that the people taking them were getting an unknown,unprescribed dose of powerful medications.
Anybody remember Pycnogenol ? About 15 years ago it was the WONDER Food Supplement - bark scrapings from a tree in North America by Native Americans - not heard much about it recently.
