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Smoking and the breast cancer risk gene BRCA2 combine to "enormously" increase the chance of developing lung cancer, a study of 27,000 people has suggested.
The research, published in the journal Nature, found the gene could double the likelihood of getting lung cancer.
And some men and women faced a far greater risk, a team at the Institute of Cancer Research in London said.
Cancer Research UK suggested drugs targeted at breast cancer may work in some lung cancers.
The links between variants of the BRCA genes and breast cancer are well established - a diagnosis led Hollywood actress Angelina Jolie to have a preventative double mastectomy - but it has also been linked with an increased risk of other cancers affecting women such as ovarian cancer and prostate cancer in men.
http://www.bbc.co.uk/news/health-27634006
The research, published in the journal Nature, found the gene could double the likelihood of getting lung cancer.
And some men and women faced a far greater risk, a team at the Institute of Cancer Research in London said.
Cancer Research UK suggested drugs targeted at breast cancer may work in some lung cancers.
The links between variants of the BRCA genes and breast cancer are well established - a diagnosis led Hollywood actress Angelina Jolie to have a preventative double mastectomy - but it has also been linked with an increased risk of other cancers affecting women such as ovarian cancer and prostate cancer in men.
http://www.bbc.co.uk/news/health-27634006