Sitagliptin side effect !!

hmgvs

New Member
Relationship to Diabetes
Type 2
Pronouns
She/Her
Type 2 diabetis. I was on metformin for 3 years, suffered badly with diarrhea so doctor changed me to Sitagliptin with small dose of metformin. 3 weeks later hubby had to take me to A&E with severe stomach pains spreading to back, so bad I was on the verge of fainting with the pain. Was in there 10 hours, had scans, xrays etc & all they found was a small chest infection probably from a bout of Covid I'd had 2 months earlier. The excruciating pains went but was replaced by a nagging pain which was worse depending on what I ate & drunk (I don't drink alcohol!) I could only eat small portions & often felt nauseas, I also became very tired but just put this down to my meds & diabetes. 2 months later the pains were a lot worse, saw doctor & he has arranged scans (3 week wait). My own investigating online shows I have all the signs of pancreatitis, blood test results seem to confirm this (looked at by a friend who is a medical Bio Scientist working for NHS in cancer screening) Remembered reading something about pancreatitis in the leaflet with Sitagliptin so got it out & re-read. It say - in the huge list of side effects - may cause pancreatitis !!! Tried to contact Diabetic nurse for advice but no reply after 2 days so I decided to stop taking Sitagliptin straight away and went back onto just metformin, the same dose as I'd been on before. Been following a liquid only diet , no fats & limited sugar for the last 10 days & pains seem to be improving. Starting to introduce small amounts of low fat & sugar normal foods in the last couple of days and so far all is well so hopefully that will have been the problem. I'm just hoping that this pancreatitis episode was a one off & won't be repetitive. and the scans don't reveal anything else. Diabetic nurse agrees it was probably the Sitagliptin and has now marked in my records that I’m allergic to it!
 
Last edited:
All medications can have side effects, best to read the leaflet before taking as it will tell you what to watch out for
 
Oh my goodness @hmgvs 😱

How awful for you! Sorry to hear you had such terrible pain. really hope everything settles down for you now.

Pancreatitis is listed on the NHS website as a serious but fortunately rare side effect.


Thankfully there are multiple classes of diabetes meds you can try these days, though I can completely understand if you were a little nervous about trying something else. Reactions like the one you had are pretty rare.
 
I've just come off of sitagliptin. I was only on it a few weeks, I had a 7 day headache and stomach pain that was gradually getting worse. I m interested to know what you take with Metformin instead . I'm waiting for blood results before I add something else in. Or change altogether.
Hope you pick. Up soon.
 
Back
Top