`Second-fiddle` player in diabetes found to be central villain

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Northerner

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Washington: A protein long believed to have a minor role in type 2 diabetes is, in fact, a central player in the development of the condition, American researchers say.

Working with mice, a team of researchers at the Johns Hopkins Children`s Center discovered that a protein called EPAC2 - deemed a second-fiddle player up until now - is actually an important regulator of insulin that appears to work by nudging insulin-secreting cells of the pancreas to ramp up production of the sugar-regulating hormone when the body needs it most.

Until now, EPAC2 was suspected of playing a merely supporting role as a signaling molecule, but scientists remained uncertain why and how that mattered, if at all.

http://zeenews.india.com/news/healt...abetes-found-to-be-central-villain_21389.html
 
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