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- Relationship to Diabetes
- Type 1
Through a longitudinal study, researchers from the US and Finland have identified changes that take place in the gut microbiome as infants develop type 1 diabetes.
The team, led by Ramnik Xavier from the Broad Institute and Massachusetts General Hospital, followed a cohort of 33 infants genetically at risk for type 1 diabetes from birth to age three and regularly characterized their gut microbiomes. As they reported in Cell, Host & Microbe today, the researchers found that while the composition of the gut microbiome varied between infants, it was fairly stable over time within an individual. But infants who progressed to type 1 diabetes experienced a drop in microbial diversity just prior to diagnosis.
https://www.genomeweb.com/metabolic...microbiome-alterations-linked-type-1-diabetes
The team, led by Ramnik Xavier from the Broad Institute and Massachusetts General Hospital, followed a cohort of 33 infants genetically at risk for type 1 diabetes from birth to age three and regularly characterized their gut microbiomes. As they reported in Cell, Host & Microbe today, the researchers found that while the composition of the gut microbiome varied between infants, it was fairly stable over time within an individual. But infants who progressed to type 1 diabetes experienced a drop in microbial diversity just prior to diagnosis.
https://www.genomeweb.com/metabolic...microbiome-alterations-linked-type-1-diabetes