Researchers Identify New Genetic and Epigenetic Contributors to Diabetes

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Comparison of fat cells in mice and men hints at how genes and environment conspire to produce disease.

An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say. Their findings reveal that obesity-induced changes to the epigenome -- reversible chemical "tags" on DNA -- are surprisingly similar in mice and humans, and might provide a new route to prevention and treatment of the disease, which affects hundreds of millions worldwide.

http://www.diabetesincontrol.com/ar...netic-and-epigenetic-contributors-to-diabetes
 
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