Bronco Billy
Moderator
- Relationship to Diabetes
- Parent of person with diabetes
Please note, this research has been approved.
A team of researchers is looking for women who had diabetes before becoming pregnant.
We would like to talk to women with diabetes about our proposed project to better understand the effect of maternal glucose levels on the very early stages of pregnancy. Currently we know very little about how glucose affects the first critical stage of pregnancy implantation of the embryo into the wall of the womb. This is possibly the most vulnerable point in reproduction as the embryo must immediately start to make a placenta - the organ that extracts the nutrients and oxygen needed to grow from the mother's blood. During the early phases of placental development, there is two-way communication between maternal cells and those of the embryo. We believe that if the cells of the womb see too much glucose at this stage, the embryo won't have the right instructions to make a placenta properly. This could mean that the placenta can't provide the right amount of nutrition for the fetus to grow properly, so the baby is too small or too big at birth.
We hope that the information gained from our proposed project will help give better advice about glucose control to women planning to get pregnant and will allow the development of interventions to help women with diabetes have the best possible pregnancy outcome. We would like to discuss our questions, ideas and approaches to check that they are of relevance and importance to women with diabetes.
We will be asking for feedback over the phone and by email so it could be anyone nationally. We would like to speak to several women about the relevancy and importance of the research project and to hear their views on the proposed outcome measures. We would also like 2-3 women to review the lay summary to ensure it is clear and understandable.
In the future, if the women consent to their contact details being kept, we would like to get their input at the end of the study on how best to inform people of the research findings.
Please contact Katharine Cresswell (Patient Involvement Project Manager) - Katharine.cresswell@mft.nhs.uk 0161 276 8943 or Melissa Westwood (Lead Researcher) - Melissa.westwood@manchester.ac.uk
Deadline: 18th November 2019
A team of researchers is looking for women who had diabetes before becoming pregnant.
We would like to talk to women with diabetes about our proposed project to better understand the effect of maternal glucose levels on the very early stages of pregnancy. Currently we know very little about how glucose affects the first critical stage of pregnancy implantation of the embryo into the wall of the womb. This is possibly the most vulnerable point in reproduction as the embryo must immediately start to make a placenta - the organ that extracts the nutrients and oxygen needed to grow from the mother's blood. During the early phases of placental development, there is two-way communication between maternal cells and those of the embryo. We believe that if the cells of the womb see too much glucose at this stage, the embryo won't have the right instructions to make a placenta properly. This could mean that the placenta can't provide the right amount of nutrition for the fetus to grow properly, so the baby is too small or too big at birth.
We hope that the information gained from our proposed project will help give better advice about glucose control to women planning to get pregnant and will allow the development of interventions to help women with diabetes have the best possible pregnancy outcome. We would like to discuss our questions, ideas and approaches to check that they are of relevance and importance to women with diabetes.
We will be asking for feedback over the phone and by email so it could be anyone nationally. We would like to speak to several women about the relevancy and importance of the research project and to hear their views on the proposed outcome measures. We would also like 2-3 women to review the lay summary to ensure it is clear and understandable.
In the future, if the women consent to their contact details being kept, we would like to get their input at the end of the study on how best to inform people of the research findings.
Please contact Katharine Cresswell (Patient Involvement Project Manager) - Katharine.cresswell@mft.nhs.uk 0161 276 8943 or Melissa Westwood (Lead Researcher) - Melissa.westwood@manchester.ac.uk
Deadline: 18th November 2019