Regular use of acid reflux drugs linked to heightened risk of type 2 diabetes

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Northerner

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Regular use of acid reflux drugs, known as proton pump inhibitors, or PPIs for short, is linked to a heightened risk of developing type 2 diabetes, finds research published online in the journal Gut.

And the longer these drugs are taken, the greater the risk seems to be, the findings show, prompting the researchers to advise that people taking these drugs for 2 or more years should have regular blood glucose check-ups to screen for diabetes.

PPIs are used to treat acid reflux, peptic ulcers, and indigestion. They are among the top 10 most commonly used drugs worldwide. Long-term use has been linked to an increased risk of bone fractures, chronic kidney disease, gut infections and stomach cancer.

In 2014, the global prevalence of type 2 diabetes was 8.5%, and the researchers wanted to find out if the widespread use of PPIs and the high prevalence of diabetes might be linked.

 
Ah fun. I have to take omeprazole as I’m on naproxen long term so now I have to deal with possible complications of taking a drug that I need to deal with the complications of the drug that I actually need o_O
 
Ah fun. I have to take omeprazole as I’m on naproxen long term so now I have to deal with possible complications of taking a drug that I need to deal with the complications of the drug that I actually need o_O
Indeed. When I stopped taking statins because of joint/muscle pain that I had attributed to arthritis, I was also able to stop the meloxicam to deal with this pain (very occasional paracetamol and/or ibuprofen gel is enough), and also stop the omeprazole tp protect from the meloxicam. So 3 drugs stopped for one! Got to be good.
 
I was in a similar position with omeprazole in the months after diagnosis - taking it to counter the effects of other drugs! 🙄
 
Acid reflux is far commoner in people who are overweight or obese. People who are overweight or obese are far more likely to develop Type 2 diabetes. So they take Omeprazole. So what? You could equally blame Gaviscon. Or Rennies.

I had to stop Omeprazole because the GP spotted the lethargy and muscle weakness I was moaning about was due to Magnesium deficiency caused by Omeprazole, so I soon bounced back to my normal self. Until, of course, PLS started rotting my motor neurones. And, like just about everyone, I was taking Omeprazole to counter side effects from other medication.
 
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