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- Relationship to Diabetes
- Type 1
Managing type 2 diabetes typically involves losing weight, exercise and medication, but new research by Dr. Makoto Fukuda and colleagues at Baylor College of Medicine and other institutions suggests that there may be other ways to control the condition through the brain. The researchers have discovered a mechanism in a small area of the brain that regulates whole-body glucose balance without affecting body weight, which suggests the possibility that modulating the mechanism might help keep blood sugar levels in a healthy range.
"A growing body of evidence strongly suggests that the brain is a promising yet unrealized therapeutic target for type 2 diabetes, as it has been shown that it can regulate glucose metabolism," said Fukuda, assistant professor of pediatrics-nutrition at Baylor. "To further materialize this concept, it is of great interest to identify potentially druggable molecular targets mediating the brain's antidiabetic effects."
"A growing body of evidence strongly suggests that the brain is a promising yet unrealized therapeutic target for type 2 diabetes, as it has been shown that it can regulate glucose metabolism," said Fukuda, assistant professor of pediatrics-nutrition at Baylor. "To further materialize this concept, it is of great interest to identify potentially druggable molecular targets mediating the brain's antidiabetic effects."
Rap1 controls the body's sugar levels from the brain
Researchers have discovered a mechanism in a small area of the brain that regulates whole-body glucose balance without affecting body weight.
www.sciencedaily.com
