Prenatal Smoking Linked to Less Childhood T1D Risk

[Northerner]

Researchers published the study covered in this summary on Preprints with The Lancet as a preprint that has not yet been peer reviewed.

Key Takeaways​

• In a nationwide Swedish study of more than 3 million people, prenatal exposure to smoking was significantly associated with a reduced risk for developing type 1 diabetes during childhood, but not after the offspring turned 25 years old.
• Young adults who smoked did not have a reduced risk for developing type 1 diabetes, and the evidence showed a signal that the risk for adult-onset type 1 diabetes may have increased in this group.

Why This Matters​

• Prenatal exposure to smoking has previously been linked to a reduced risk of type 1 diabetes in children compared with those with nonsmoking mothers, but no prior reports have addressed whether this protection continues into adulthood or applies to adults who themselves smoke.
• This is the first study to investigate maternal smoking during pregnancy in relation to type 1 diabetes incidence in offspring beyond childhood.

The authors cautioned that the clinical significance of their findings was "difficult to see" considering the many adverse effects from smoking during pregnancy. They instead highlighted that their findings add to understanding the etiology of type 1 diabetes.

Prenatal Smoking Linked to Less Childhood T1D Risk

Maternal smoking significantly linked with a lower risk for incident type 1 diabetes in children, but not in adulthood. Smoking by young adults showed a signal for a link to incident type 1 diabetes.

www.medscape.com

 

[MikeyBikey]

This conjecture seems a total waste of time, money and brain power to me as smoking has so many risks. I wonder if the off spring have an increased risk of Type II in adulthood as smoking itself increases the risk of developing Type II but I am nor suggesting that any effort is put into researching it. Have woken in the early hours yet again with phantom pain I think this needs more research as if variations of "mindfulness" don't help consultants and GPs just tend to change or increase dose of painkillers!

Edit: I know of two suicides related to phantom pain which shows how serious a problem it is!

 

[Northerner]

This conjecture seems a total waste of time, money and brain power to me as smoking has so many risks. I wonder if the off spring have an increased risk of Type II in adulthood as smoking itself increases the risk of developing Type II but I am nor suggesting that any effort is put into researching it. Have woken in the early hours yet again with phantom pain I think this needs more research as if variations of "mindfulness" don't help consultants and GPs just tend to change or increase dose of painkillers!

Edit: I know of two suicides related to phantom pain which shows how serious a problem it is!

Indeed, there are far more pressing problems to dedicate research effort to. I hope you can find something that works for you, it's certainly an issue that has been known about probably for centuries

 

[littlevoice359]

How that research got funding is beyond me. I think, personally, that researchers should pay more attention to the old adage - correlation does not equal causation.

 

[EmmaL76]

Pretty sure my mum smoked when she was pregnant with me, I remember her telling me nurses would wheel them out for a cigarette or maybe even that they could smoke in the hospital well anyhow she packed up when she had my younger sister cuz she’s always been the favourite and I got diabetes and she didn’t so my research tells me it’s the other way round so if your reading this mother… hope you have learnt a valuable life lesson😡

 

[Deleted member 21371]

Maybe the focus will be looking at any particular effect the smoking may have had, and finding if a way to produce the same result without actually smoking may be beneficial.
Maybe it'll relate to a "bad" gene switched off by the effects of smoking that could be recreated?
Any information is always good.