Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Research shows that postprandial glucagon levels increase over time in children with newly diagnosed Type 1 diabetes, and are associated with worsening glycaemic control, suggesting an adjunctive treatment approach.
Glucagon levels rose by 51% within the first year of follow-up, and by 160% at 5 years, say Siri Fredheim (Herlev Hospital, Copenhagen, Denmark) and study co-authors.
“Notably, hyperglucagonaemia in response to liquid mixed-meal feeding is evidently established shortly after disease onset and seems to persist after several years with diabetes”, they write in Diabetologia.
The team obtained the results in 129 children, aged an average of 10 years at the time of diagnosis, who were initially in partial remission (postprandial C-peptide >300 pmol/L). All children underwent a liquid mixed-meal test at 1, 3, 6 and 12 months after diagnosis, and 40 were also tested at 60 months.
http://www.news-medical.net/news/20...-to-glycaemic-control-in-Type-1-diabetes.aspx
Glucagon levels rose by 51% within the first year of follow-up, and by 160% at 5 years, say Siri Fredheim (Herlev Hospital, Copenhagen, Denmark) and study co-authors.
“Notably, hyperglucagonaemia in response to liquid mixed-meal feeding is evidently established shortly after disease onset and seems to persist after several years with diabetes”, they write in Diabetologia.
The team obtained the results in 129 children, aged an average of 10 years at the time of diagnosis, who were initially in partial remission (postprandial C-peptide >300 pmol/L). All children underwent a liquid mixed-meal test at 1, 3, 6 and 12 months after diagnosis, and 40 were also tested at 60 months.
http://www.news-medical.net/news/20...-to-glycaemic-control-in-Type-1-diabetes.aspx