Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Having diabetes doubles a person's risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart enzyme, which leads to death of pacemaker cells in the heart, abnormal heart rhythm, and increased risk of sudden death in diabetic mice following a heart attack.
"Many studies have shown that patients with diabetes are at especially high risk for dying from a myocardial infarction (heart attack). Our study provides new evidence that this excess mortality could involve a pathway where oxidized CaMKII enzyme plays a central role," says Mark Anderson, M.D., Ph.D., UI professor, chair, and department executive officer of internal medicine, and senior author of the study published Feb. 15 in the Journal of Clinical Investigation.
http://www.sciencedaily.com/releases/2013/02/130217085255.htm
"Many studies have shown that patients with diabetes are at especially high risk for dying from a myocardial infarction (heart attack). Our study provides new evidence that this excess mortality could involve a pathway where oxidized CaMKII enzyme plays a central role," says Mark Anderson, M.D., Ph.D., UI professor, chair, and department executive officer of internal medicine, and senior author of the study published Feb. 15 in the Journal of Clinical Investigation.
http://www.sciencedaily.com/releases/2013/02/130217085255.htm