Pfizer's vaccine "90% effective"

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Eddy Edson

Eddy Edson

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mikeyB said:
Might be 90% effective, but is it more than 90% safe?
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This is the only info I see out there:


No serious safety concerns have been observed, the company said.

Pfizer plans to ask the Food and Drug Administration for emergency authorization of the two-dose vaccine later this month, after it has collected the recommended two months of safety data.
 
I will only belive it when it has been approved and released.
 
grovesy said:
I will only belive it when it has been approved and released.
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This is one of the ones that's mRNA, I think. So it's using a new and exciting vaccine platform (at least for humans, though maybe it's been used for animal vaccines before).
 
I think we need to be cautious here.
This is still lightening fast for drug development.
I have heard that the vaccine needs to be stored at -90 degrees Celsius which is going to be a significant barrier to overcome if true.
 
pm133 said:
I think we need to be cautious here.
This is still lightening fast for drug development.
I have heard that the vaccine needs to be stored at -90 degrees Celsius which is going to be a significant barrier to overcome if true.
Click to expand...
They have also said need 2 doses 21-28 days apart.
 
Safety would be more important to me than effectiveness. There's apparently a myth going around, that it's impossible to test long term safety of a vaccine without long term (10-15yrs) testing.
 
pm133 said:
I think we need to be cautious here.
This is still lightening fast for drug development.
I have heard that the vaccine needs to be stored at -90 degrees Celsius which is going to be a significant barrier to overcome if true.
Click to expand...
Yes - I heard -80C which is surely going to cause problems in some parts of the world, even the most capable 😱 What's the temp when it goes into your arm? 😱 🙂
 
Northerner said:
Yes - I heard -80C which is surely going to cause problems in some parts of the world, even the most capable 😱 What's the temp when it goes into your arm? 😱 🙂
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They'll probably need to use some form of sealed storage unit containing something like an alcohol and dry ice slushy mixture to get to those temperatures. That's how I used to get to those temperatures when I worked in a Chemistry lab. The problem won't be getting vaccines stored at that temperature as much as the knock-on effect of distribution requirements.
Presumably it just needs stored at low temperature to stop it decomposing over a period of a few hours or so but will be OK to be warmed to room temp before administering.

Still, this is positive news.
 
pm133 said:
I think we need to be cautious here.
This is still lightening fast for drug development.
I have heard that the vaccine needs to be stored at -90 degrees Celsius which is going to be a significant barrier to overcome if true.
Click to expand...
its going to hurt going into the arm at that temperature..................
 
pm133 said:
Presumably it just needs stored at low temperature to stop it decomposing over a period of a few hours or so but will be OK to be warmed to room temp before administering.
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They're saying it should be fine at normal fridge temperatures for a day (or maybe a week or two, depending on which story you read).
 
Trouble with new drugs and vaccines is when they do go wrong, it's virtually impossible to get those repsonsible to admit any fault. These types of cases can go on for decades before any admission of guilt is acknowledged and even then, it doesn't put things back to where they were before, no matter what the amount of compenstion paid.

In 1996, Pfizer needed a human trial for what it hoped would be a pharmaceutical "blockbuster", a broad spectrum antibiotic that could be taken in tablet form. The US-based company sent a team of its doctors into the Nigerian slum city of Kano in the midst of an appaling meningitis epidemic to perform what it calls a "humanitarian mission". However the accusers claim it was an unlicensed medical trial on critically-ill children.

Nine years on and the lawyers efforts have finally been rewarded with a reported $75m (£50m) settlement.

www.independent.co.uk

Pfizer to pay £50m after deaths of Nigerian children in drug

Out of court settlement in the case that inspired 'The Constant Gardener'
www.independent.co.uk www.independent.co.uk
 
Amity Island said:
Trouble with new drugs and vaccines is when they do go wrong, it's virtually impossible to get those repsonsible to admit any fault. These types of cases can go on for decades before any admission of guilt is acknowledged and even then, it doesn't put things back to where they were before, no matter what the amount of compenstion paid.

In 1996, Pfizer needed a human trial for what it hoped would be a pharmaceutical "blockbuster", a broad spectrum antibiotic that could be taken in tablet form. The US-based company sent a team of its doctors into the Nigerian slum city of Kano in the midst of an appaling meningitis epidemic to perform what it calls a "humanitarian mission". However the accusers claim it was an unlicensed medical trial on critically-ill children.

Nine years on and the lawyers efforts have finally been rewarded with a reported $75m (£50m) settlement.

www.independent.co.uk

Pfizer to pay £50m after deaths of Nigerian children in drug

Out of court settlement in the case that inspired 'The Constant Gardener'
www.independent.co.uk www.independent.co.uk
Click to expand...

I'm absolutely not a conspiracy theorist but reading Chemistry World over many years and seeing how many reports there were of most big pharma companies being repeatedly hauled up in court and fined for all manner of malpractice, I will be quite happy to sit back and let others take this vaccine first.
I am particularly worried about the speed of progress through the trial phases. Desperation for a "cure" and an indecent lust for money means that this has the potential for widescale disaster written all over it. My spidey-senses tell me to hold off on this for a while after the vaccine hits the market.
 
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